Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Definitions of myalgic encephalomyelitis and chronic fatigue syndrome
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
[[Category:Definitions]] Over the course of three decades, many '''definitions''' or case criteria have been developed to diagnose either [[myalgic encephalomyelitis]] (ME), [[chronic fatigue syndrome]] (CFS), or [[Systemic Exertion Intolerance Disease]] (SEID) which is an [[ME/CFS]] criteria. Some of these definitions or criteria are meant only to be diagnostic, i.e., used in a clinical setting to aid in diagnosis and some are meant to be used both in a clinical and research setting. Each of these criteria and case definitions have been considered lacking in complete reliability and accuracy. Another change in the definition is assumed when medical research uncovers more of the pathophysiology of this illness.<ref name="Williams, 2014">{{Cite journal | last1 = Williams | first1 = Yolonda J. | author-link1 = Yolonda Williams | last2 = Jantke | first2 = Rachel L. | authorlink2 = Rachel Jantke | last3 = Jason | first3 = Leonard A. | authorlink3 = Leonard Jason | title = Chronic Fatigue Syndrome: Case Definitions and Diagnostic Assessment | journal = New York State Psychologist | volume = 26 | issue = 4 | page = 41β45 | date = 2014 | pmid = 27594717 }}</ref> ==ME== * 1986 [[Ramsay definition]]<ref>{{Cite web | url = https://www.cfids-me.org/ramsay86.html | title = Ramsay's Definition of M.E. | last = | first = | authorlink = | date = 1986 | website = cfids-me.org| archive-url = | archive-date = |url-status = | access-date=2020-11-13}}</ref> * 2007 [[Nightingale definition]]<ref>[http://www.nightingale.ca/documents/Nightingale_ME_Definition_en.pdf The Nightingale Definition of Myalgic Encephalomyelitis (M.E.)]</ref> * 2011 [[International Consensus Criteria]] (ICC)<ref>{{Cite journal | last = Carruthers | first = Bruce M. | authorlink = Bruce Carruthers | last2 = van de Sande | first2 = Marjorie I. | authorlink2 = Marjorie van de Sande | last3 = De Meirleir | first3 = Kenny L. | author-link3 = Kenny De Meirleir | last4 = Klimas | first4 = Nancy G. | author-link4 = Nancy Klimas | last5 = Broderick | first5 = Gordon | author-link5 = Gordon Broderick | last6 = Mitchell | first6 = Terry | author-link6 = Terry Mitchell | last7 = Staines | first7 = Donald | author-link7 = Donald Staines | last8 = Powles | first8 = A.C. Peter | author-link8 = A C Peter Powles | last9 = Speight | first9 = Nigel | author-link9 = Nigel Speight | last10 = Vallings | first10 = Rosamund | author-link10 = Rosamund Vallings | last11 = Bateman | first11 = Lucinda | author-link11 = Lucinda Bateman | last12 = Baumgarten-Austrheim | first12 = Barbara | author-link12 = Barbara Baumgarten-Austrheim | last13 = Bell | first13 = David | author-link13 = David Bell | last14 = Carlo-Stella | first14 = Nicoletta | author-link14 = Nicoletta Carlo-Stella | last15 = Chia | first15 = John | author-link15 = John Chia | last16 = Darragh | first16 = Austin | author-link16 = Austin Darragh | last17 = Jo | first17 = Daehyun | author-link17 = Daehyun Jo | last18 = Lewis | first18 = Donald | author-link18 = Donald Lewis | last19 = Light | first19 = Alan | author-link19 = Alan Light | last20 = Marshall-Gradisnik | first20 = Sonya | author-link20 = Sonya Marshall-Gradisnik | last21 = Mena | first21 = Ismael | author-link21 = Ismael Mena | last22 = Mikovits | first22 = Judy | author-link22 = Judy Mikovits | last23 = Miwa | first23 = Kunihisa | author-link23 = Kunihisa Miwa | last24 = Murovska | first24 = Modra | author-link24 = Modra Murovska | last25 = Pall | first25 = Martin | author-link25 = Martin Pall | last26 = Stevens | first26 = Staci | author-link26 = Staci Stevens | date = 2011-08-22 | title=Myalgic encephalomyelitis: International Consensus Criteria | url = https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2796.2011.02428.x|journal=Journal of Internal Medicine|language=en|volume=270|issue=4 | pages = 327β338|doi=10.1111/j.1365-2796.2011.02428.x|issn=0954-6820|pmc=3427890|pmid=21777306|via=}}</ref> * 2014 [[London criteria]]<ref name="Londoncriteria">{{Citation | url =http://www.axfordsabode.org.uk/me/mecrit2014.htm|archive-url=http://web.archive.org/web/20150923181011/http://www.axfordsabode.org.uk/me/mecrit2014.htm|archive-date=2015-09-23|url-status=dead | title = Myalgic Encephalomyelitis (ME). Criteria and clinical guidelines. 2014 | date = Oct 15, 2014 | last = Howes | first = Sandra | authorlink = Sandra Howes | last2 = Goudsmit | first2 = Ellen M. | author2link = Ellen Goudsmit | last3 = Shepherd | first3 = Charles |author3link = Charles Shepherd}}</ref> The [[International Consensus Criteria]] is currently used in some research and by few clinicians in some countries. [[Ramsay definition]], [[Nightingale definition]] and [[London criteria]] are currently not in use. ==CFS== * 1988 [[CDC]] case definition ("[[Holmes criteria]]")<ref>{{Cite journal | last = Holmes | first = G.P. | authorlink = Gary Holmes | last2 = Kaplan | first2 = J.E. | authorlink2 = | last3 = Gantz | first3 = N.M. | author-link3 = | last4 = Komaroff | first4 = A.L. | author-link4 = Anthony Komaroff | last5 = Schonberger | first5 = L.B. | author-link5 = | last6 = Straus | first6 = S.E. | author-link6 = Stephen Straus | last7 = Jones | first7 = J.F. |last8 = Dubois | first8 = R.E. | last9 = Cunningham-Rundles | first9 = C. | date = Mar 1988 | title = Chronic fatigue syndrome: a working case definition | url =https://pubmed.ncbi.nlm.nih.gov/2829679/|journal=Annals of Internal Medicine|volume=108|issue=3 | pages = 387β389|doi=10.7326/0003-4819-108-3-387|issn=0003-4819|pmc=|pmid=2829679|access-date=|quote=|via=}}</ref> * 1991 [[Oxford criteria]]*<ref>{{Cite journal | last = Sharpe | first = M.C. | authorlink = Michael Sharpe | last2 = Archard | first2 = L.C. | authorlink2 = | last3 = Banatvala | first3 = J.E. | author-link3 = | last4 = Borysiewicz | first4 = L.K. | author-link4 = | last5 = Clare | first5 = A.W. | author-link5 = Anthony Cleare | last6 = David | first6 = A. | author-link6 = Anthony David | last7 = Edwards | first7 = R.H. | last8 = Hawton | first8 = K.E. | last9 = Lambert | first9 = H.P. | date = Feb 1991 | title = A report--chronic fatigue syndrome: guidelines for research | url = https://pubmed.ncbi.nlm.nih.gov/1999813/|journal=Journal of the Royal Society of Medicine|volume=84|issue=2 | pages = 118β121|doi=|issn=0141-0768|pmc=1293107|pmid=1999813|access-date=|quote=|via=}}</ref> * 1994 CDC case definition ("[[Fukuda criteria]]")* (CDC-1994)<ref>{{Cite journal | last = Fukuda | first = K. | authorlink = Keiji Fukuda | last2 = Straus | first2 = S.E. | authorlink2 = Stephen Straus | last3 = Hickie | first3 = I. | author-link3 = Ian Hickie | last4 = Sharpe | first4 = M.C. | author-link4 = Michael Sharpe | last5 = Dobbins | first5 = J.G. | author-link5 = | last6 = Komaroff | first6 = A. | author-link6 = Anthony Komaroff | date = 1994-12-15 | title = The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group | url = https://pubmed.ncbi.nlm.nih.gov/7978722/|journal=Annals of Internal Medicine|volume=121|issue=12 | pages = 953β959|doi=10.7326/0003-4819-121-12-199412150-00009|issn=0003-4819|pmc=|pmid=7978722|access-date=|quote=|via=}}</ref> * 2005 CDC case definition ("[[Reeves criteria]]")*<ref>{{Cite journal | last = Reeves | first = William C. | authorlink = William Reeves | last2 = Wagner | first2 = Dieter | authorlink2 = | last3 = Nisenbaum | first3 = Rosane | authorlink3 = | last4 = Jones | first4 = James F. | author-link4 = | last5 = Gurbaxani | first5 = Brian | author-link5 = | last6 = Solomon | first6 = Laura | author-link6 = | last7 = Papanicolaou | first7 = Dimitris A. | last8 = Unger | first8 = Elizabeth R. | last9 = Vernon | first9 = Suzanne D. | date = 2005-12-15 | title = Chronic fatigue syndrome--a clinically empirical approach to its definition and study | url = https://pubmed.ncbi.nlm.nih.gov/16356178/|journal=BMC medicine|volume=3|issue= | pages = 19|doi=10.1186/1741-7015-3-19|issn=1741-7015|pmc=1334212|pmid=16356178|access-date=|quote=|via=}}</ref> The [[Holmes criteria]] is currently not in use. The [[Oxford criteria]] has been very recently retired but was heavily used in the UK by researchers and some clinicians. The [[Fukuda criteria]] is used in research by several countries including the US and sometimes in the UK. [[Reeves criteria]] is currently being used in the [[NIH Post-Infectious ME/CFS Study]] but overall it is not in use. ==Combined (ME/CFS)== * 2021, [[NICE ME/CFS diagnostic criteria 2021|NICE ME/CFS diagnostic criteria]]<ref name="niceng206">{{Cite web | url = https://www.nice.org.uk/guidance/ng206 | title = Myalgic Encephalomyelitis (or Encephalopathy)/Chronic Fatigue Syndrome:diagnosis and management. NICE guideline. | last = NICE Guideline Development Group|first = | authorlink = | publisher = [[National Institute for Health and Care Excellence]] | date = 2021-10-29}}</ref> * 2003 [[Canadian Consensus Criteria]] (CCC)<ref>{{Cite journal | last = Carruthers | first = Bruce M. | last2 = Jain | first2 = Anil Kumar | last3 = Meirleir | first3 = Kenny L. De | last4 = Peterson | first4 = Daniel L. | last5 = Klimas | first5 = Nancy G. | last6 = Lerner | first6 = A. Martin | last7 = Bested | first7 = Alison C. | last8 = Flor-Henry | first8 = Pierre | last9 = Joshi | first9 = Pradip | date = 2003-01-01 | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | url =https://doi.org/10.1300/J092v11n01_02|journal=Journal of Chronic Fatigue Syndrome|volume=11|issue=1 | pages = 7β115|doi=10.1300/J092v11n01_02|issn=1057-3321}}</ref> * 2007 [[NICE CFS/ME diagnostic criteria 2007|NICE CFS/ME guidelines]]*<ref>{{Cite web | url = https://www.nice.org.uk/guidance/CG53/chapter/1-Guidance#diagnosis | title = Chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy): diagnosis and management {{!}} Guidance | last = | first = | authorlink = | date = 2017 | website = nice.org.uk| archive-url = | archive-date = |url-status = | access-date=2020-11-13}}</ref> The [[Canadian Consensus Criteria]] is sometimes used by clinicians and for research in many countries but has not been officially adopted by most countries including the US. [[NICE guidelines]] are used by clinicians in the [[United Kingdom|UK]]. Note: [[ME/CFS]] (or CFS/ME in parts of Europe) is the acronym now used in the US, UK, and some other countries. =='SEID'== * 2015 [[IOM|Institute of Medicine]] (IOM) diagnostic criteria<ref>{{Cite web | url = https://www.nationalacademies.org/hmd/~/media/Files/Report%20Files/2015/MECFS/MECFS_ProposedDiagnosticCriteria?_ga=1.14761526.1865741811.1437002921 | title = Proposed Diagnostic Criteria | last = Institute of Medicine | first = | authorlink = | date = 2015 | website = nationalacademies.org| archive-url = | archive-date = |url-status = | access-date=2020-11-13}}</ref> * The name "Systemic Exertion Intolerance Disease" (SEID) was proposed in conjunction with this criteria, but was not adopted.<ref>{{Cite web | url = https://www.cdc.gov/me-cfs/healthcare-providers/diagnosis/iom-2015-diagnostic-criteria.html | title = IOM 2015 Diagnostic Criteria {{!}} Diagnosis {{!}} Healthcare Providers {{!}} Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | date = 2018-11-08 | website = [[Centers for Disease Control and Prevention]]|language=en-us|access-date=2019-04-12}}</ref> *Currently used for by the CDC for ME/CFS diagnosis<ref name="CDC-symptoms">{{Cite web | url = https://www.cdc.gov/me-cfs/symptoms-diagnosis/symptoms.html | title = Symptoms {{!}} Myalgic Encephalomyelitis/Chronic Fatigue Syndrome|website=[[Centers for Disease Control and Prevention]] | date = Jan 27, 2021|access-date = 2021-02-25}}</ref> The IOM criteria is an ME/CFS criteria proposed for use in the [[United States|US]] in clinical settings. The [[NIH Post-Infectious ME/CFS Study]] is using this criteria along with [http://me-pedia.org/wiki/NIH_Post-Infectious_ME/CFS_Study#Selection_criteria three other criteria]. The [[Centers for Disease Control and Prevention]] (CDC) outlines the IOM diagnostic criteria on their ME/CFS page [https://www.cdc.gov/me-cfs/healthcare-providers/diagnosis/iom-2015-diagnostic-criteria.html ''IOM 2015 Diagnostic Criteria'']. ==Note on Definition flaws== Definitions with a asterisk (*) are considered to be by most ME/CFS patients, many ME/CFS patients groups, and several ME/CFS researchers as being seriously flawed in that these criteria capture individuals suffering from [[chronic fatigue]] and not [[chronic fatigue syndrome]], [[myalgic encephalomyelitis]] or [[Systemic Exertion Intolerance Disease]]. ==Comparison== *2001, A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome<ref name="DeBecker2001">{{Cite journal | last1 = De Becker | first1 = P | author-link1 = Pascale De Becker | last2 = McGregor | first2 = N | authorlink2 = Neil McGregor | last3 = De Meirleir | first3 = K | authorlink3 = Kenny de Meirleir | title = A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome | journal = Journal of Internal Medicine | volume = 250 | issue = 3 | page = 234-240 | date =Sep 2001 | pmid = 11555128 | url = https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2796.2001.00890.x?sid=nlm%3Apubmed}}</ref> - [https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2796.2001.00890.x?sid=nlm%3Apubmed (Full text)] *2003, Variability in diagnostic criteria for chronic fatigue syndrome may result in substantial differences in patterns of symptoms and disability<ref>{{Cite journal | issn = 0163-2787| volume = 26 | issue = 1| pages = 3β22| last1 = Jason | first1 = Leonard A. | last2 = Helgerson | first2 = Jena | last3 = Torres-Harding | first3 = Susan R. | last4 = Carrico | first4 = Adam W. | last5 = Taylor | first5 = Renee R.| title = Variability in diagnostic criteria for chronic fatigue syndrome may result in substantial differences in patterns of symptoms and disability| journal = Evaluation & the Health Professions| date = Mar 2003 | pmid = 12629919 | url = https://www.researchgate.net/profile/Leonard-Jason/publication/10862361_Variability_In_Diagnostic_Criteria_For_Chronic_Fatigue_Syndrome_May_Result_In_Substantial_Differences_In_Patterns_Of_Symptoms_And_Disability/links/0046351acfbfc3573a000000/Variability-In-Diagnostic-Criteria-For-Chronic-Fatigue-Syndrome-May-Result-In-Substantial-Differences-In-Patterns-Of-Symptoms-And-Disability.pdf}}</ref> - [https://www.researchgate.net/profile/Leonard-Jason/publication/10862361_Variability_In_Diagnostic_Criteria_For_Chronic_Fatigue_Syndrome_May_Result_In_Substantial_Differences_In_Patterns_Of_Symptoms_And_Disability/links/0046351acfbfc3573a000000/Variability-In-Diagnostic-Criteria-For-Chronic-Fatigue-Syndrome-May-Result-In-Substantial-Differences-In-Patterns-Of-Symptoms-And-Disability.pdf (Full text)] *2012, Contrasting case definitions for chronic fatigue syndrome, Myalgic Encephalomyelitis/chronic fatigue syndrome and myalgic encephalomyelitis<ref name="pmid22158691">{{Cite journal | doi = 10.1177/0163278711424281| issn = 1552-3918| volume = 35 | issue = 3| pages = 280β304| last1 = Jason | first1 = Leonard A. | last2 = Brown | first2 = Abigail | last3 = Clyne | first3 = Erin | last4 = Bartgis | first4 = Lindsey | last5 = Evans | first5 = Meredyth | last6 = Brown | first6 = Molly| title = Contrasting case definitions for chronic fatigue syndrome, Myalgic Encephalomyelitis/chronic fatigue syndrome and myalgic encephalomyelitis| journal = Evaluation & the Health Professions| date = Sep 2012 | pmid = 22158691 | url = https://www.researchgate.net/profile/Leonard-Jason/publication/51868660_Contrasting_Case_Definitions_for_Chronic_Fatigue_Syndrome_Myalgic_EncephalomyelitisChronic_Fatigue_Syndrome_and_Myalgic_Encephalomyelitis/links/00b4951acddb075753000000/Contrasting-Case-Definitions-for-Chronic-Fatigue-Syndrome-Myalgic-Encephalomyelitis-Chronic-Fatigue-Syndrome-and-Myalgic-Encephalomyelitis.pdf}}</ref> - [https://www.researchgate.net/profile/Leonard-Jason/publication/51868660_Contrasting_Case_Definitions_for_Chronic_Fatigue_Syndrome_Myalgic_EncephalomyelitisChronic_Fatigue_Syndrome_and_Myalgic_Encephalomyelitis/links/00b4951acddb075753000000/Contrasting-Case-Definitions-for-Chronic-Fatigue-Syndrome-Myalgic-Encephalomyelitis-Chronic-Fatigue-Syndrome-and-Myalgic-Encephalomyelitis.pdf (Full text)] *2015, Accurate diagnosis of myalgic encephalomyelitis and chronic fatigue syndrome based upon objective test methods for characteristic symptoms<ref name="Twisk2015">{{Cite journal | last = Twisk|first = Frank NM | date = 2015 | title=Accurate diagnosis of myalgic encephalomyelitis and chronic fatigue syndrome based upon objective test methods for characteristic symptoms |url =http://www.wjgnet.com/2222-0682/full/v5/i2/68.htm|journal=World Journal of Methodology|language=en|volume=5|issue=2 | pages = 68|doi=10.5662/wjm.v5.i2.68|issn=2222-0682|pmc = 4482824|pmid=26140274}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482824/ (Full text)] *2015, Chronic Fatigue Syndrome and Myalgic Encephalomyelitis: Toward An Empirical Case Definition - [[Case Definition Comparison - Graph 1]]<ref name="PMC4443921">{{Cite journal | last = Jason | first = Leonard A. | authorlink = Leonard Jason | last2 = Kot | first2 = Bobby | authorlink2 = | last3 = Sunnquist | first3 = Madison | authorlink3 = Madison Sunnquist | last4 = Brown | first4 = Abigail | author-link4 = Abigail Brown | last5 = Evans | first5 = Meredyth | author-link5 = Meredyth Evans | last6 = Jantke | first6 = Rachel | author-link6 = Rachel Jantke | last7 = Williams | first7 = Yolonda | last8 = Furst | first8 = Jacob | author-link8 = | last9 = Vernon | first9 = Suzanne D. | author-link9 = Suzanne Vernon | date = 2015 | title=Chronic Fatigue Syndrome and Myalgic Encephalomyelitis: Toward An Empirical Case Definition | url =https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443921/|journal=Health psychology and behavioral medicine|volume=3|issue=1 | pages = 82β93|doi=10.1080/21642850.2015.1014489|issn=2164-2850|pmc=4443921|pmid=26029488}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443921/ (Full text)] *2016, Chronic Fatigue Syndrome versus Systemic Exertion Intolerance Disease<ref name="Jason, Sunn, 2015">{{Cite journal | last1 = Jason | first1 = L.A. | author-link1 = Leonard Jason | last2 = Sunnquist | first2 = M. | authorlink2 = Madison Sunnquist | last3 = Brown | first3 = A. | authorlink3 = Abigail Brown | last4 = Newton | first4 = J.L. | author-link4 = Julia Newton | last5 = Strand | first5 = E.B. | author-link5 = Elin Strand | last6 = Vernon | first6 = S.D. | author-link6 = Suzanne Vernon | title = Chronic fatigue syndrome versus systemic exertion intolerance disease | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556426 | journal = Fatigue: Biomedicine, Health & Behavior | volume = 3 | issue = 3 | page = 127-141 | date = 2015 | pmid = | pmc = PMC4556426 | doi = 10.1080/21641846.2015.1051291 }}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556426 (Full text)] *2017, Patients diagnosed with Myalgic encephalomyelitis/chronic fatigue syndrome also fit systemic exertion intolerance disease criteria ([[Lily Chu]]), ([[Jane Norris]]), ([[Ian Valencia]]) & ([[Jose Montoya]]) - [https://www.tandfonline.com/doi/full/10.1080/21641846.2017.1299079 (Full text)] *2017, A Comparison of Case Definitions for Myalgic Encephalomyelitis and Chronic Fatigue Syndrome<ref name="Sunnquist, 2017">{{Cite journal | last1 = Sunnquist | first1 = Madison | author-link1 = Madison Sunnquist | last2 = Jason | first2 = Leonard | authorlink2 = Leonard Jason | last3 = Nehrke | first3 = Pamela | authorlink3 = | last4 = Goudsmit | first4 = Ellen | author-link4 = Ellen Goudsmit | title = A Comparison of Case Definitions for Myalgic Encephalomyelitis and Chronic Fatigue Syndrome | journal = Journal of Chronic Diseases and Management | volume = 2 | issue = 2 | page = 1013 | date = 2017 | pmid = 29104961 | pmc = PMC5663312 | doi = | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663312}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663312 (Full text)] *2017, [[How have selection bias and disease misclassification undermined the validity of myalgic encephalomyelitis/chronic fatigue syndrome studies?]]<ref name="Nacul2017">{{Cite journal | last = Nacul|first = Luis | authorlink = Luis Nacul | last2 = Lacerda | first2 = Eliana M | authorlink2 = Eliana Lacerda | last3 = Kingdon | first3 = Caroline C | authorlink3 = Caroline Kingdon | last4 = Curran | first4 = Hayley | author-link4 = Hayley Curran | last5 = Bowman | first5 = Erinna W | author-link5 = Erinna Bowman | date = Mar 1, 2017 | title = How have selection bias and disease misclassification undermined the validity of myalgic encephalomyelitis/chronic fatigue syndrome studies? | url = https://doi.org/10.1177/1359105317695803|journal=[[Journal of Health Psychology]]|language=en|volume=|issue= | pages = 1359105317695803|doi=10.1177/1359105317695803|issn=1359-1053|pmc=5581258|pmid=28810428|quote=|via=}}</ref> - [https://journals.sagepub.com/doi/10.1177/1359105317695803 (Full text)] ==Narrowest and broadest diagnostic criteria == The retired [[Oxford criteria]] for CFS selected the highest number of patients as having CFS, and the [[Canadian Consensus Criteria|Canadian definition]] of ME/CFS selects the smallest number of patients, leading to radically different results in research. Nacul et al. (2017) stated: ::"For every 15 patients selected under Oxford criteria, 14 will be false positives when compared to [[Canadian Consensus Criteria]]. The [[Pace trial]] and [[FINE trial]] used Oxford criteria."<br > ::"When studies using the broad Oxford criteria (Sharpe et al., 1991) were excluded, a virtual disappearance of effect for [[graded exercise therapy]] (GET), [[cognitive behavioral therapy|cognitive behaviour therapy]] (CBT) and other psychological therapies recommended by the NICE guidelines (National Institute for Health and Care Excellence (NICE), 2007) was revealed."<ref name="Nacul2017"/> {{See also|Research bias in ME/CFS}} == Learn more == *[http://www.TandFonline.com/doi/abs/10.1080/21641846.2015.1051291?journalCode=rftg20 CFS vs SEID - Tandfonline] The ''Four-symptom criteria'' is noted. *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443921/ Chronic Fatigue Syndrome and Myalgic Encephalomyelitis: Toward An Empirical Case Definition]<ref name="PMC4443921"/> See: Graph - 1 *[http://www.healthrising.org/blog/2015/07/19/excluding-factors-jason-critiques-the-iom-definition-for-mecfs/ Excluding Factors: Jason Critiques the IOM Definition for ME/CFS - Health Rising - Cort Johnson] The ''Four-symptom criteria'' is noted. == See also == *[[Misdiagnosis of myalgic encephalomyelitis and chronic fatigue syndrome]] *[[Primer_for_the_public#Disease_names_and_acronyms_around_the_world|Primer for the public (''Disease names and acronyms around the world'' section)]] *[[Case Definition Comparison - Graph 1]] *[[DePaul Symptom Questionnaire]] *[[Four-symptom criteria]] ==References== {{reflist}} [[Category:Disease names and definitions]] [[Category:Lists]]
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Templates used on this page:
MediaWiki:Colon-separator/en
(
view source
)
MediaWiki:Seealso/en
(
view source
)
Template:Citation
(
edit
)
Template:Cite journal
(
edit
)
Template:Cite web
(
edit
)
Template:Full stop
(
edit
)
Template:GetFallback
(
edit
)
Template:LangSwitch
(
edit
)
Template:Main other
(
edit
)
Template:Reflist
(
edit
)
Template:See also
(
edit
)
Template:Uselang
(
edit
)
Module:Check for unknown parameters
(
edit
)
Module:Citation/CS1
(
edit
)
Module:Citation/CS1/COinS
(
edit
)
Module:Citation/CS1/Configuration
(
edit
)
Module:Citation/CS1/Date validation
(
edit
)
Module:Citation/CS1/Identifiers
(
edit
)
Module:Citation/CS1/Utilities
(
edit
)
Module:Citation/CS1/Whitelist
(
edit
)
Module:No globals
(
edit
)
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs