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1953 Maryland outbreak
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== Symptoms == [[File:Distribution of symptoms during the 1953 Rockville, Maryland outbreak.png|thumb|Distribution of symptoms during the 1953 Rockville, Maryland outbreak<ref name="Shelokov, 1957" />]] The investigators authored an article for the ''New England Journal of Medicine'' and noted the following core symptoms<ref name="Shelokov, 1957" />: * localized muscular weakness ([[paresis]]) * [[Neck stiffness|stiffness of the neck]] and [[Back stiffness|back]] * [[headache]] * [[diarrhea]] * temperature elevation and instability of [[body temperature]] The outbreak was deemed to resemble other [[list of outbreaks|outbreaks]] of poliomyelitis-like illnesses in hospitals around the same time, including the [[1934 Los Angeles atypical polio outbreak|Los Angeles County Hospital in 1934]]. [[Epidemic neuromyasthenia]] became the final diagnosis.<ref name="Shelokov, 1957" /> Often a minor illness characterized by [[Flu-like symptoms|flu-like malaise]], [[Myalgia|achiness]] and low-grade [[fever]] proceeded by several days to up to two weeks the development of a full-blown symptom complex (i.e., involving muscle weakness and partial [[paralysis]]). If the prodromal period persisted, symptoms might include diarrhea, [[nausea]] and [[vomiting]] and in some cases, severe [[respiratory illness]]es.<ref name="Shelokov, 1957" /> Additional symptoms included [[sore throat]], [[postural headache]], [[abdominal pain]], [[menstrual irregularities]], and [[Eye pain|pain on eye]] motion.<ref name="Shelokov, 1957" />
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