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== האם ME תמיד מתפרצת בעקבות זיהום? == מספר קטן של ארגוני צדקה לחולי [https://migrate.me-pedia.org/wiki/Myalgic_encephalomyelitis ME] למשל [[The Hummingbirds' Foundation for ME]] ימחזיקים בדעה שמיאליג'יק אנספלומיאליטס נגרמת תמיד על ידי [[וירוס]], ואילו [https://migrate.me-pedia.org/wiki/Chronic_fatigue_syndrome לתסמונת התשישות הכרונית] יכולים להיות טריגרים לא-ויראליים, [https://migrate.me-pedia.org/wiki/Bacterial_infection זיהומים חיידקיים] או לא.<ref name="hfme">{{Cite web|url=http://www.hfme.org/methemedicalfacts.htm | title = M.E.: The medical facts | last = Bassett | first = Jodi | authorlink=Jodi Bassett | date = 2010 | website = [[The Hummingbirds' Foundation for ME]]|archive-url=|archive-date=|access-date=2019-02-09|quote=Myalgic encephalomyelitis is a systemic acutely acquired illness initiated by a virus infection which is characterised by post encephalitic damage to the brain stem; a nerve centre through which many spinal nerve tracts connect with higher centres in the brain in order to control all vital bodily functions – this is always damaged in M.E. (Hence the name Myalgic Encephalomyelitis.) The CNS is diffusely injured at several levels, these include the cortex, the limbic system, the basal ganglia, the hypothalamus and areas of the spinal cord and its appendages. This persisting multilevel central nervous system (CNS) dysfunction, and in particular, inconsistent CNS dysfunction is undoubtedly both the chief cause of disability in M.E. and the most critical in the definition of the entire disease process.}}</ref> ראה גם תיאורית ההתפרצות הויראלית<ref name="Chu" />
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