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Quercetin
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==Chronic fatigue syndrome== Quercetin's antioxidant and anti-inflammatory properties are thought to be important in resolving the pathophysiology of ME/CFS. Additionally, a 2009 study by J. Mark Davis, et al. (2008)<ref name="Davis2008">{{Citation| doi = 10.1152/ajpregu.90925.2008| issn = 0363-6119| volume = 296 | issue = 4| pages = 1071-R1077| last1 = Davis | first1 = J. Mark | last2 = Murphy | first2 = E. Angela | last3 = Carmichael | first3 = Martin D. | last4 = Davis | first4 = Ben| title = Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance| journal = American Journal of Physiology - Regulatory, Integrative and Comparative Physiology| access-date = 2016-11-09| date = 2009-04-01| url = http://ajpregu.physiology.org/content/296/4/R1071 | pmid = 19211721}}</ref> showed markers of mitochondrial biogenesis in mouse skeletal muscle and brain, and on endurance exercise tolerance after a week of quercetin in their food. Luteolin is another flavonoid antioxidant which is common place. Flavonoids are believed to be poorly absorbed due to bring rapidly metabolized and excreted. There remains no evidence that polyphenols (of which flavonoids are subset of) have any relevance on the body. Additionally, although antioxidants in the diet are required to be healthy, there is considerable debate on which antioxidants are health promoting, in what amounts and if they can prevent or help chronic diseases.
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