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[[File:Michael Maes.png|200px|thumb|right|Source:Linkedin.com ]] '''Michael Maes''', M.D., Ph.D., developed the [[Neuro-Inflammatory and Oxidative Fatigue]] (NIOF) Theory as a cause for ME/CFS.<ref name="Maes, 2015" /> He currently works at the Department of Psychiatry, Chulalongkorn University, Bangkok, Thailand.<ref name="researchgate">{{Cite web|url=https://www.researchgate.net/profile/Michael_Maes2 | title = Michael Maes {{!}} M.D., Ph.D. {{!}} Chulalongkorn University, Bangkok {{!}} Department of Psychiatry|website=ResearchGate|language=en|access-date=2019-09-13}}</ref> Other work associations include IMPACT Strategic Research Center, Barwon Health, Deakin University, School of Medicine, Geelong, Victoria, [[Australia]] and the Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, [[Brazil]].<ref name="researchgate" /><ref name="revitalis">http://revitalis.nl/?team=prof-dr-michael-maes</ref> While living in [[Belgium]], he served as a clinician at MCare4U Outpatient Clinics in Antwerp.<ref name="Maes2006">{{Cite journal | last = Maes | first = Michael | authorlink = | last2 = Mihaylova | first2 = Ivana | authorlink2 = | last3 = Leunis | first3 = Jean-Claude | author-link3 = Jean-Claude Leunis | date = Oct 2006 | title = Chronic fatigue syndrome is accompanied by an IgM-related immune response directed against neopitopes formed by oxidative or nitrosative damage to lipids and proteins|url=https://www.ncbi.nlm.nih.gov/pubmed/17159817|journal=Neuro Endocrinology Letters|volume=27|issue=5 | pages = 615β621|doi=|issn=0172-780X|pmc=|pmid=17159817|access-date=|quote=|via=}}</ref> His special interests include: Behavorial Systems Biology, [[depression|major depression]], inflammatory illnesses and [[chronic fatigue syndrome]].<ref name="gs">{{Cite web|url=https://scholar.google.com/citations?user=1wzMZ7UAAAAJ&hl=en&oi=ao | title = Michael Maes - Citations|website=Google Scholar|access-date=2019-08-28}}</ref> ==Neuro-Inflammatory and Oxidative Fatigue (NIOF) Theory== In 2015, Maes developed a new case definition of [[myalgic encephalomyelitis]]/[[chronic fatigue syndrome]] (ME/CFS) called [[Neuro-Inflammatory and Oxidative Fatigue]] (NIOF) "based on pattern recognition methods and using neuro-immune, inflammatory, oxidative and nitrosative stress (neuro-IO&NS) biomarkers as external validating criteria." These biomarkers include "[[Immuglobulin M|IgM]] / [[Immuglobulin A|IgA]] responses against LPS ([[lipopolysaccharide]]s) of gut commensal bacteria ([[leaky gut]]), IgM responses to O&NS modified neoepitopes, autoimmunity to serotonin, plasma interleukin-1 ([[interleukin 1|IL-1]]) and serum neopterin." Maes sees a "significant overlap between NIOF and chronic fatigue syndrome although NIOF criteria were much more restrictive."<ref name="Maes, 2015" /> Professor Maes proposes the ME/CFS, as well as other chronic diseases, can be treated by lessening the [[Neuro-Inflammatory and Oxidative Fatigue]] with foods and supplements that decrease inflammation and repair [[leaky gut]] such as [[curcumin]], [[N-acetyl-cysteine]] ββ(NAC), [[glutamine]], [[zinc]], and [[omega 3 fatty acid hypothesis|omega-3 fats]].<ref name="revitalis" /> ==Books== *2011, ''[[Nooit Meer Moe]]'' (English translation: 'Tired No More, CFS Unmasked') <ref name="Michael Maes, 2011">{{Cite book | author = Michael Maes| title = Nooit-Mer-Moe | trans-title = Never Tired| language = nl| date = Apr 2011| publisher = Zorro Publisher| isbn = 9789461680013 | url = https://www.bol.com/nl/p/nooit-meer-moe/1001004011100533/ }}</ref> ==Notable studies== *2006, Increased serum [[Immunoglobulin A|IgA]] and IgM against LPS of enterobacteria in chronic fatigue syndrome (CFS): indication for the involvement of gram-negative enterobacteria in the etiology of CFS and for the presence of an increased gut-intestinal permeability.<ref name="MaesM20060927">{{Cite journal | last1 = Maes | first1 = Michael | authorlink1 = Michael Maes | last2 = Mihaylova | first2 = Ivanka | authorlink2 = Ivanka Mihaylova | last3 = Leunis | first3 = JC | authorlink3 = Jean-Claude Leunis| title = Increased serum IgA and IgM against LPS of enterobacteria in chronic fatigue syndrome (CFS): indication for the involvement of gram-negative enterobacteria in the etiology of CFS and for the presence of an increased gut-intestinal permeability| journal = J Affect Disord | volume = 99 |issue = 1-3| pages = 237-240 | url = https://doi.org/10.1016%2Fj.jad.2006.08.021 | date = Sep 27, 2006 | pmid = 17007934 | doi = 10.1016/j.jad.2006.08.021}}</ref> - [https://doi.org/10.1016%2Fj.jad.2006.08.021 (Abstract)] *2008, Normalization of [[Intestinal permeability|leaky gut]] in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: Effects of age, duration of illness and the translocation of LPS from gram-negative bacteria<ref name="Maes, 2008">{{Cite journal | last1 = Maes | first1 = Michael | authorlink1 = Michael Maes | last2 = Leunis | first2 = JC | authorlink2 = Jean-Claude Leunis| title = Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: Effects of age, duration of illness and the translocation of LPS from gram-negative bacteria| journal = Neuro endocrinology letters | volume = 26 | issue = 6 | pages = 902-910| url = https://pubmed.ncbi.nlm.nih.gov/19112401 | date = 2008 | pmid = 19112401 }}</ref> - [https://www.researchgate.net/publication/23709068_Normalization_of_leaky_gut_in_chronic_fatigue_syndrome_CFS_is_accompanied_by_a_clinical_improvement_Effects_of_age_duration_of_illness_and_the_translocation_of_LPS_from_gram-negative_bacteria (Abstract)] *2009, Chronic Fatigue Syndrome: la bΓͺte noire of the Belgian Health Care System<ref name="Maes2009">{{Cite journal | last = Maes | first = Michael | authorlink = Michael Maes | last2 = Twisk | first2 = Frank NM | authorlink2 = Frank Twisk | authorlink3 = | date = Apr 29, 2009 | title = Chronic fatigue syndrome: la bΓͺte noire of the Belgian health care system|url=http://www.me-foreningen.info/wp-content/uploads/2016/09/CFS-la-b%C3%AAte-noire-of-the-Belgian-Health-Care-System-Maes-Twisk.pdf | journal=Neuro Endocrinology Letters|volume=30|issue=3|pages=300β311|issn=0172-780X|pmid=19855351|quote=|via=}}</ref> - [http://www.me-foreningen.info/wp-content/uploads/2016/09/CFS-la-b%C3%AAte-noire-of-the-Belgian-Health-Care-System-Maes-Twisk.pdf (Full text)] *2009, A review on cognitive behavorial therapy (CBT) and graded exercise therapy (GET) in myalgic encephalomyelitis (ME) chronic fatigue syndrome (CFS): CBT/GET is not only ineffective and not evidence-based, but also potentially harmful for many patients with ME/CFS<ref name="Twisk2009">{{Cite journal | last1 = Twisk | first1 = Frank NM | authorlink1 = Frank Twisk | last2 = Maes | first2 = Michael | authorlink2 = Michael Maes | title = A review on cognitive behavorial therapy (CBT) and graded exercise therapy (GET) in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS): CBT/GET is not only ineffective and not evidence-based, but also potentially harmful for many patients with ME/CFS.| journal = Neuroendocrinology Letters | volume = 30 | issue = 3| pages = 284β299 | date = 2009 | pmid = 19855350 | url = https://www.researchgate.net/profile/Frank_Twisk/publication/38034776_A_review_on_cognitive_behavorial_therapy_CBT_and_graded_exercise_therapy_GET_in_myalgic_encephalomyelitis_ME_chronic_fatigue_syndrome_CFS_CBTGET_is_not_only_ineffective_and_not_evidence-based_but_also/links/02e7e524d8e90ac344000000/A-review-on-cognitive-behavorial-therapy-CBT-and-graded-exercise-therapy-GET-in-myalgic-encephalomyelitis-ME-chronic-fatigue-syndrome-CFS-CBT-GET-is-not-only-ineffective-and-not-evidence-based-but.pdf}}</ref> - [https://www.researchgate.net/profile/Frank_Twisk/publication/38034776_A_review_on_cognitive_behavorial_therapy_CBT_and_graded_exercise_therapy_GET_in_myalgic_encephalomyelitis_ME_chronic_fatigue_syndrome_CFS_CBTGET_is_not_only_ineffective_and_not_evidence-based_but_also/links/02e7e524d8e90ac344000000/A-review-on-cognitive-behavorial-therapy-CBT-and-graded-exercise-therapy-GET-in-myalgic-encephalomyelitis-ME-chronic-fatigue-syndrome-CFS-CBT-GET-is-not-only-ineffective-and-not-evidence-based-but.pdf (Full text)] *2009, [[Coenzyme Q10]] deficiency in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early [[Causes of death|mortality]] in ME/CFS due to cardiovascular disorder<ref name="Maes2009CoQ10">{{Cite journal | last = Maes | first = Michael | authorlink = Michael Maes | last2 = Mihaylova | first2 = Ivanka | author-link3 = Marta Kubera | last3 = Kubera | first3 = Marta | last4 = Uytterhoeven | first4 = Marc | last5 = Vrydags | first5 = Nicolas | last6 = Bosmans | first6 = Eugene | date = 2009 | title = Coenzyme Q10 deficiency in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder |url =https://www.ncbi.nlm.nih.gov/pubmed/20010505|journal=Neuro Endocrinology Letters|volume=30|issue=4 | pages = 470β476|issn=0172-780X|pmid=20010505|via=}}</ref> - [[pubmed:20010505|(Abstract)]] *2011, Increased [[Immunoglobulin A|IgA]] responses to the LPS of commensal bacteria is associated with [[inflammation]] and activation of cell-mediated immunity in chronic fatigue syndrome<ref name="MaesM20111002">{{Cite journal | last1 = Maes | first1 = Michael | authorlink1 = Michael Maes | last2 = Twisk | first2 = Frank N | authorlink2 = Frank Twisk | last3 = Kubera | first3 = M | authorlink3 = Marta Kubera | last4 =Ringel | first4 = K | authorlink4 = Karl Ringel | last5 = Leunis | first5 = JC | authorlink5 = Jean-Claude Leunis | last6 = Geffard | first6 = M | authorlink6 = Michel Geffard| title = Increased IgA responses to the LPS of commensal bacteria is associated with inflammation and activation of cell-mediated immunity in chronic fatigue syndrome| journal = J Affect Disord | volume = 136 | issue =3 | pages = 909-17 | url = https://pubmed.ncbi.nlm.nih.gov/21967891 | date = Oct 2, 2011 | pmid = 21967891 | doi = 10.1016/j.jad.2011.09.010 }}</ref> - [https://pubmed.ncbi.nlm.nih.gov/21967891 (Abstract)] *2012, Evidence for [[inflammation]] and activation of cell-mediated immunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): increased [[Interleukin 1|interleukin-1]], [[TNF-alpha|tumor necrosis factor-Ξ±]], PMN-elastase, [[lysozyme]] and [[neopterin]].<ref name="MaesTwisk2012">{{Cite journal | last = Maes | first = Michael | authorlink = Michael Maes | last2 = Twisk | first2 = Frank N.M. | authorlink2 = Frank Twisk | authorlink3 = Marta Kubera | last3 = Kubera | first3 = Marta | last4 = Ringel | first4 = Karl | date = Feb 2012 | title = Evidence for inflammation and activation of cell-mediated immunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Increased interleukin-1, tumor necrosis factor-Ξ±, PMN-elastase, lysozyme and neopterin | url =http://linkinghub.elsevier.com/retrieve/pii/S0165032711005301|journal=Journal of Affective Disorders|volume=136|issue=3 | pages = 933β939|pmid=21975140|doi=10.1016/j.jad.2011.09.004|issn=0165-0327|via=}}</ref> - [[pubmed:21975140|(Abstract)]] *2012, Myalgic Encephalomyelitis (ME), Chronic Fatigue Syndrome (CFS), and Chronic Fatigue (CF) are distinguished accurately: results of supervised learning techniques applied on clinical and inflammatory data<ref name="Maes2012CF">{{Cite journal | last = Maes | first = Michael | authorlink = Michael Maes | last2 = Twisk | first2 = Frank N.M. | authorlink2 = Frank Twisk | last3 = Johnson | first3 = Cort | authorlink3 = Cort Johnson | date = Dec 2012 | title = Myalgic Encephalomyelitis (ME), Chronic Fatigue Syndrome (CFS), and Chronic Fatigue (CF) are distinguished accurately: Results of supervised learning techniques applied on clinical and inflammatory data|url=http://linkinghub.elsevier.com/retrieve/pii/S0165178112001400|journal=Psychiatry Research|volume=200|issue=2-3 | pages = 754β760|doi=10.1016/j.psychres.2012.03.031|issn=0165-1781|via=}}</ref> - [[pubmed:22521895|(Abstract)]] *2013, In myalgic encephalomyelitis/chronic fatigue syndrome, increased autoimmune activity against 5-HT is associated with immuno-inflammatory pathways and bacterial translocation<ref name="Maes, 2013">{{Cite journal | last1 = Maes | first1 = Michael | authorlink1 = Michael Maes | last2 = Ringel | first2 = Karl | authorlink2 = Karl Ringel | last3 = Kubera | first3 = Marta | authorlink3 =Marta Kubera | last4 = Anderson | first4 = George | authorlink4 = | last5 = Morris | first5 = Gerwyn | authorlink5 = Gerwyn Morris | last6 = Galacki | first6 = Piotr | authorlink6 = | last7 = Geffard | first7 = Michel | authorlink7 = Michel Geffard| title = In myalgic encephalomyelitis/chronic fatigue syndrome, increased autoimmune activity against 5-HT is associated with immuno-inflammatory pathways and bacterial translocation| journal = Journal of Affective Disorders | volume = 150 | issue = 2 | page = 223-230| date = Sep 5, 2013| url = https://doi.org/10.1016%2Fj.jad.2013.03.029 | doi = 10.1016/j.jad.2013.03.029}}</ref> - [http://www.jad-journal.com/article/S0165-0327(13)00254-1/abstract (Abstract)] *2013, Case definitions and diagnostic criteria for Myalgic Encephalomyelitis and Chronic fatigue Syndrome: from clinical-consensus to evidence-based case definitions<ref name="Morris, 2013">{{Cite journal | last1 = Morris | first1 = Gerwyn | authorlink1 = Gerwyn Morris | last2 = Maes | first2 = Michael | authorlink2 = Michael Maes| title = Case definitions and diagnostic criteria for Myalgic Encephalomyelitis and Chronic fatigue Syndrome: from clinical-consensus to evidence-based case definitions| journal = Neuro Endocrinology Letters | volume = 34 | issue = 3 | pages = 185-199| date = 2013 | pmid = 23685416| url = http://www.nel.edu/archive_issues/o/34_3/NEL340313R01_Morris--Maes.pdf | doi = }}</ref> - [http://www.nel.edu/archive_issues/o/34_3/NEL340313R01_Morris--Maes.pdf (Full text)] *2014, Review Article -Mitochondrial dysfunctions in Myalgic Encephalomyelitis / chronic fatigue syndrome explained by activated immuno-inflammatory, oxidative and nitrosative stress pathways<ref name="Morris, G. & Maes, M., 2014">{{Cite journal | last= Morris | first = Gerwyn | authorlink1 = Gerwyn Morris | last2 = Maes | first2 = Michael | authorlink2 = Michael Maes | title = Mitochondrial dysfunctions in Myalgic Encephalomyelitis / chronic fatigue syndrome explained by activated immuno-inflammatory, oxidative and nitrosative stress pathways| journal = Metabolic Brain Disease | volume = 29 | issue =1| pages = 19-36 | date = 2014 | pmid = 24557875 | doi = 10.1007/s11011-013-9435-x | url = https://pubmed.ncbi.nlm.nih.gov/24557875/}}</ref> - [https://pubmed.ncbi.nlm.nih.gov/24557875/ (Abstract)] *2014, The emerging role of autoimmunity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/cfs)<ref name="Morris, 2014">{{Cite journal | last1 = Morris | first1 = Gerwyn | authorlink1 = Gerwyn Morris | last2 = Berk | first2 = Michael | authorlink2 = Michael Berk | last3 = Galacki | first3 = Piotr | authorlink3 = Piotr Galacji | last4 = Maes | first4 = Michael | authorlink4 = Michael Maes | title = The emerging role of autoimmunity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/cfs)| journal = Molecular Neurobiology | volume = 49 | issue = 2 | pages = 741-756 | date = 2014 | url = https://doi.org/10.1007%2Fs12035-013-8553-0 | doi = 10.1007/s12035-013-8553-0}}</ref> - [https://doi.org/10.1007%2Fs12035-013-8553-0 (Abstract)] *2014, Oxidative and Nitrosative Stress and Immune-Inflammatory Pathways in Patients with Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS)<ref name="<ref name=">{{Cite journal | last1 = Morris | first1 = Gerwyn | authorlink1 = Gerwyn Morris | last2 = Maes | first2 = Michael | authorlink2 = Michael Maes | title = Oxidative and Nitrosative Stress and Immune-Inflammatory Pathways in Patients with Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS)| journal = Current Neuropharmacology | volume = 12 | issue = 2 | pages = 168β185 | date = 2014 | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964747 | pmc = PMC3964747| doi=10.2174/1570159X11666131120224653}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964747/ (Full Text)] *2014, Evidence for the existence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with and without abdominal discomfort (irritable bowel) syndrome<ref name="Maes2014IBS">{{Cite journal | title = Evidence for the existence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with and without abdominal discomfort (irritable bowel) syndrome | date = 2014 |url=https://pubmed.ncbi.nlm.nih.gov/25433843/|journal=Neuro Endocrinology Letters|volume=35|issue=6 | pages = 445β453 | last = Maes | first = Michael | authorlink = Michael Maes | last2 = Leunis | first2 = Jean-Claude | authorlink2 = Jean-Claude Leunis | last3 = Geffard | first3 = Michel | authorlink3 = | last4 = Berk | first4 = Michael | authorlink4 = Michael Berk|doi=|pmc=|pmid=25433843|access-date=|issn=0172-780X|quote=|via=}}</ref> - [https://www.nel.edu/userfiles/articlesnew/NEL350614A01.pdf (Full text)] *2015, A new case definition of Neuro-Inflammatory and Oxidative Fatigue (NIOF), a neuroprogressive disorder, formerly known as chronic fatigue syndrome or Myalgic Encephalomyelitis: results of multivariate pattern recognition methods and external validation by neuro-immune biomarkers.<ref name="Maes, 2015">{{Cite journal | last1 = Maes | first1 = Michael | authorlink1 = Michael Maes| title = A new case definition of Neuro-Inflammatory and Oxidative Fatigue (NIOF), a neuroprogressive disorder, formerly known as chronic fatigue syndrome or Myalgic Encephalomyelitis: results of multivariate pattern recognition methods and external validation by neuro-immune biomarkers.| journal = Neuro endocrinology letters | volume = 36 | issue = 4 | pages = 320-329| date = 2015 | url = http://www.ncbi.nlm.nih.gov/pubmed/26454487 | pmid = 26454487 }}</ref> - [http://www.ncbi.nlm.nih.gov/pubmed/26454487 (Abstract)] *2015, Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses<ref name="Morris, 2015">{{Cite journal | last1 = Morris | first1 = Gerwyn | authorlink1 = Gerwyn Morris | last2 = Berk | first2 = Michael | authorlink2 = Michael Berk | last3 = Walder | first3 = K | authorlink3 = | last4 = Maes | first4 = Michael | authorlink4 = Michael Maes | title = Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses.| journal = BMC Medicine | volume = 13 | issue = | pages = 28 | date = 2015 | url = https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-014-0259-2 | doi = 10.1186/s12916-014-0259-2}}</ref> - [https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-014-0259-2 (Full Text)] *2016, Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome<ref name="Morris, 23Jun2016">{{Cite journal | last1 = Morris | first1 = Gerwyn | authorlink1 = Gerwyn Morris | last2 = Berk | first2 = Michael | authorlink2 = Michael Berk | last3 = Klein | first3 = H. | authorlink3 = | last4 = Walder | first4 = K. | authorlink4 = | last5 = Galacki | first5 = Piotr | authorlink5 = | last6 = Maes | first6 = Michael | authorlink6 = Michael Maes | title = Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome| journal = Molecular Neurobiology | volume = 54 | issue = 6 | pages = 4271-4291 | date = Jun 23, 2016 | url = http://link.springer.com/article/10.1007/s12035-016-9975-2 | doi = 10.1007/s12035-016-9975-2}}</ref> - [http://link.springer.com/article/10.1007/s12035-016-9975-2 (Abstract)] *2016, The role of microbiota and intestinal permeability in the pathophysiology of autoimmune and neuroimmune processes with an emphasis on Inflammatory Bowel Disease, Type 1 Diabetes and Chronic Fatigue Syndrome<ref name="Morris, 2016">{{Cite journal | last1 = Morris | first1 = Gerwyn | authorlink1 = Gerwyn Morris | last2 = Berk | first2 = Michael | authorlink2 = Michael Berk | last3 = Carvalho | first3 = A.F. | authorlink3 = | last4 = Caso | first4 = J.R. | authorlink4 = | last5 = Sanz | first5 = Y. | authorlink5 = | last6 = Maes | first6 = Michael | authorlink6 = Michael Maes | title = The role of microbiota and intestinal permeability in the pathophysiology of autoimmune and neuroimmune processes with an emphasis on Inflammatory Bowel Disease Type 1 Diabetes and Chronic Fatigue Syndrome.| journal = Current Pharmaceutical Design | volume = 22 | issue = 40 | pages = 6058-6075 | date = 2016 | url = https://www.ncbi.nlm.nih.gov/pubmed/27634186 | pmid = 27634186}}</ref> - [https://www.ncbi.nlm.nih.gov/pubmed/27634186 (Abstract)] *2017, Mechanisms Explaining Muscle Fatigue and Muscle Pain in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a Review of Recent Findings<ref name="Morris, 2017">{{Cite journal | last1 = Morris | first1 = Gerwyn | authorlink1 = Gerwyn Morris | last2 = Maes | first2 = Michael | authorlink2 = Michael Maes | title = Mechanisms Explaining Muscle Fatigue and Muscle Pain in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a Review of Recent Findings| journal = Current Rheumatology Reports | volume = 19 | issue = 1 | pages = 1 | date = 2017| url = http://link.springer.com/article/10.1007/s11926-017-0628-x | pmid = | doi = 10.1007/s11926-017-0628-x}}</ref> - [http://link.springer.com/article/10.1007/s11926-017-0628-x (Abstract)] *2018, Recognizing the leaky gut as a trans-diagnostic target for neuro-immune disorders using clinical chemistry and molecular immunology assays<ref name="Simeonova2018">{{Cite journal | last = Simeonova | first = Denitsa | authorlink = | last2 = Ivanovska | first2 = Mariya | authorlink2 = | last3 = Murdjeva | first3 = Mariana | author-link3 = | last4 = Carvalho | first4 = Andre F. | authorlink4 = | last5 = Maes | first5 = Michael | authorlink5 = Michael Maes | date = 2018-11-15 | title = Recognizing the leaky gut as a trans-diagnostic target for neuro-immune disorders using clinical chemistry and molecular immunology assays|url=http://www.eurekaselect.com/167390/article|journal=Current Topics in Medicinal Chemistry|language=en|volume=18|issue=19|pages=1641-1655|doi=10.2174/1568026618666181115100610|issn=1568-0266|quote=|via=}}</ref> - [[pubmed:30430944|(Abstract)]] *2019, Myalgic encephalomyelitis or chronic fatigue syndrome: how could the illness develop?<ref name="Morris2019">{{Cite journal | last = Morris | first = Gerwyn | authorlink = Gerwyn Morris | last2 = Maes | first2 = Michael | authorlink2 = Michael Maes | last3 = Berk | first3 = Michael | authorlink3 = Michael Berk | last4 = Puri | first4 = Basant K. | authorlink4 = Basant Puri | authorlink5 = | date = 2019-02-13 | title = Myalgic encephalomyelitis or chronic fatigue syndrome: how could the illness develop?|url=http://link.springer.com/10.1007/s11011-019-0388-6|journal=Metabolic Brain Disease|language=en|volume=34|issue=2|pages=385-415|doi=10.1007/s11011-019-0388-6|issn=0885-7490|pmid=30758706|pmc=PMC6428797|quote=|via=}}</ref> - [https://link.springer.com/article/10.1007%2Fs11011-019-0388-6 (Full text)] *2019, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: From Pathophysiological Insights to Novel Therapeutic Opportunities<ref name="Morris2019Novel">{{Cite journal | last = Morris | first = Gerwyn | authorlink = Gerwyn Morris | last2 = Puri | first2 = Basant K. | authorlink2 = Basant Puri | last3 = Walker | first3 = Adam J. | authorlink3 = | last4 = Maes | first4 = Michael | authorlink4 = Michael Maes | last5 = Carvalho | first5 = Andre F. | authorlink5 = | last6 = Walder | first6 = Ken | authorlink6 = | last7 = Mazza | first7 = Catherine | last8 = Berk | first8 = Michael | authorlink8 = Michael Berk | date = Sep 2019 | title = Myalgic encephalomyelitis/chronic fatigue syndrome: From pathophysiological insights to novel therapeutic opportunities|url=https://linkinghub.elsevier.com/retrieve/pii/S1043661819308011|journal=Pharmacological Research|language=en|volume=148|issue=|pages=104450|doi=10.1016/j.phrs.2019.104450|pmc=|pmid=31509764|access-date=|quote=|via=}}</ref> - [[pubmed:31509764|(Abstract)]] *2019, Editorial - Is a diagnostic blood test for chronic fatigue syndrome on the horizon?<ref name="Maes2019Ed">{{Cite journal | last = Maes | first = Michael | last2 = Rodriguez | first2 = Laura Andres | last3 = Morris | first3 = Gerwyn | author-link3 = Gerwyn Morris | date = 2019-10-18 | title = Is a diagnostic blood test for chronic fatigue syndrome on the horizon?|url=https://www.tandfonline.com/doi/full/10.1080/14737159.2020.1681976|journal=Expert Review of Molecular Diagnostics|volume=19|issue=12|pages=1049-1051|doi=10.1080/14737159.2020.1681976|issn=1473-7159|pmc=|pmid=|quote=|access-date=}}</ref> - [https://www.tandfonline.com/doi/full/10.1080/14737159.2020.1681976?scroll=top&needAccess=true (Full text)] * 2021, The Reification of the Clinical Diagnosis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) as an Immune and Oxidative Stress Disorder: Construction of a Data-Driven Nomothethic Network and Exposure of ME/CFS Subgroups<ref name="Maes2021">{{Cite journal | last = Maes | first = Michael | authorlink = Michael Maes | last2 = Kubera | first2 = Marta | authorlink2 = | last3 = Stoyanova | first3 = Kristina | author-link3 = | last4 = Leunis | first4 = Jean-Claude | authorlink4 = Jean-Claude Leunis | date = 2021-01-29 | title = The Reification of the Clinical Diagnosis of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) as an Immune and Oxidative Stress Disorder: Construction of a Data-Driven Nomothethic Network and Exposure of ME/CFS Subgroups|url=https://www.preprints.org/manuscript/202101.0623/v1|journal=Current Topics in Medicinal Chemistry|volume=21|issue=16|pages=1488-1499|doi=10.2174/1568026621666210727170147|pmc=|pmid=34315375|quote=|via=Preprints}}</ref> - [https://www.researchgate.net/publication/348868130_The_reification_of_the_clinical_diagnosis_of_myalgic_encephalomyelitis_chronic_fatigue_syndrome_MECFS_as_an_immune_and_oxidative_stress_disorder_construction_of_a_data-_driven_nomothethic_network_and_ (Full text)] ==Talks and interviews== *August 2013, [https://vimeo.com/80533362 Dr Michael Maes: The Immune Pathophysiology of ME/CFS/FM] - seminar given at Emerge Australia (formerly ME/CFS Australia (Victoria) at The Alfred Hospital ==Online presence== *[http://www.ncbi.nlm.nih.gov/pubmed/?term=Maes%20M%5BAuthor%5D&cauthor=true&cauthor_uid=26454487 PubMed] *[https://www.researchgate.net/profile/Michael_Maes2 ResearchGate] *[https://www.linkedin.com/in/drmichaelmaes LinkedIn] == Learn more == *[http://cfstreatment.blogspot.com/2015/04/immune-activation-chronic-inflammation.html Onward thru the Fog blog article about Dr. Maes' research] == See also == * [[Belgium]] ==References== {{Reflist}} [[Category:Psychological paradigm critics]] [[Category:Researchers]] [[Category:Australia researchers]] [[Category:Netherlands researchers]] [[Category:Authors]] [[Category:Belgian clinicians]] [[Category:Thailand researchers]] [[Category:Belgium researchers]]
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