Editing Thiamine
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[[Thiamine pyrophosphate]] (TPP) is part of the conversion of [[acetyl coenzyme A]] (CoA). | [[Thiamine pyrophosphate]] (TPP) is part of the conversion of [[acetyl coenzyme A]] (CoA). | ||
The symptoms of thiamine deficiency include fatigue, [[paresthesia]],[[paresis|muscle weakness]], [[nausea]], changes in heart rate, and delirium. Derrick Lonsdale and Chandler Marrs argue that thiamine deficiency is more common than generally understood and an important contributor to [[dysautonomia]].<ref>{{Cite book | title=Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition|isbn=|edition=|language=English|title-link= | url = |access-date= | date = 2017 | publisher=Academic Press | editor-last = Lonsdale | editor-first = Derrick | authorlink = |editor-last2=Marrs|editor-first2=Chandler | author-link2 = |location=Cambridge, MA|pages=213–61|doi= 10.1016/B978-0-12-810387-6.00006-X|oclc=|quote=|archive-url = | last = Lonsdale | first = Derrick | last2 = Marrs | first2=Chandler}}</ref> Without adequate and usable thiamine intake, the citric acid cycle necessary for aerobic respiration cannot be completed. In its extreme forms, thiamine deficiency manifests as beriberi and Wernicke's encephalopathy. | The symptoms of thiamine deficiency include fatigue, [[paresthesia]],[[paresis|muscle weakness]], [[nausea]], changes in heart rate, and delirium. Derrick Lonsdale and Chandler Marrs argue that thiamine deficiency is more common than generally understood and an important contributor to [[dysautonomia]].<ref>{{Cite book | title=Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition|isbn=|edition=|language=English|title-link= | url = |access-date= | date = 2017 | publisher=Academic Press | editor-last = Lonsdale | editor-first = Derrick | authorlink = |editor-last2=Marrs|editor-first2=Chandler | author-link2=|location=Cambridge, MA|pages=213–61|doi= 10.1016/B978-0-12-810387-6.00006-X|oclc=|quote=|archive-url = | last = Lonsdale | first = Derrick | last2 = Marrs | first2=Chandler}}</ref> Without adequate and usable thiamine intake, the citric acid cycle necessary for aerobic respiration cannot be completed. In its extreme forms, thiamine deficiency manifests as beriberi and Wernicke's encephalopathy. | ||
== High-Dose Thiamine == | == High-Dose Thiamine == |