Indole: Difference between revisions
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'''Indoles''' are | '''Indoles''' are a type of molecule. Indole alkaloids include [[tryptophan]], an essential amino acid, [[serotonin]] and reserpine.<ref name="Ali2013">{{Cite web | url = https://www.researchgate.net/profile/Bashir_Dar3/publication/225043188_Chemistry_and_Biology_of_Indoles_and_Indazoles_A_Mini-Review/links/5cd3ca23458515712e9b6aba/Chemistry-and-Biology-of-Indoles-and-Indazoles-A-Mini-Review.pdf?origin=publication_detail | title = Chemistry and Biology of Indoles and Indazoles: A Mini-Review | last = Ali | first = Nasir Shafakat Ali, Vidya Pradhan | authorlink= | last2 = Dar | first2 = Bashir Ahmad | authorlink2 = | date = 2013-09-30|journal=Mini-Reviews in Medicinal Chemistry|volume=13|issue=12|language=en|doi=10.2174/1389557511313120009|archive-url=|archive-date=|url-status=|access-date=2019-12-18 | first3 = Vidya | last3 = Pradhan | last4 = Farooqui | first4 = Mazahar}}</ref> | ||
==Function== | ==Function== | ||
==Indole-derivative drugs== | |||
{| class="wikitable"|| | |||
!Drug !!Use | |||
|- | |||
|Lurasidone||An atypical antipsychotic used to treat schizophrenia, and [[depression]] associated with bipolar I disorder | |||
|- | |||
|Ziprasidone||Schizophrenia, bipolar mania, and agitation in patients with schizophrenia | |||
|- | |||
|Oxypertine||Unknown | |||
|- | |||
|Ziprasidone||Schizophrenia, bipolar mania, and agitation in patients with schizophrenia<ref name="drugsbank">https://www.drugbank.ca/categories/DBCAT002255</ref > | |||
|} | |||
==ME/CFS== | ==ME/CFS== | ||
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==See also == | ==See also == | ||
*[[Metabolic trap]] | *[[Metabolic trap]] | ||
*[[Indoleamine 2,3-dioxygenase]] (IDO2) | *[[Indoleamine-2,3-dioxygenase]] (IDO) | ||
*[[Indoleamine-2,3-dioxygenase]] (IDO2) | |||
*[[Tryptophan]] | *[[Tryptophan]] | ||
*[[Serotonin]] | *[[Serotonin]] | ||
==Learn more== | ==Learn more== | ||
*[https://pubchem.ncbi.nlm.nih.gov/compound/Indole Indole] - PubChem | |||
==Notable studies == | ==Notable studies == | ||
*2019, Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology - | *2019, Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology<ref name="Beloborodova2019">{{Cite journal | last = Beloborodova | first = Natalia V. | last2 = Grechko | first2 = Andrey V. | last3 = Olenin | first3 = Andrey Yu | date = 2019-06-26 | title = Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology | url = https://www.intechopen.com/online-first/metabolomic-discovery-of-microbiota-dysfunction-as-the-cause-of-pathology|journal=Metabolomics - New Insights into Biology and Medicine|language=en|doi=10.5772/intechopen.87176}}</ref> [https://doi.org/10.5772/intechopen.87176 (Full text)] | ||
==References== | ==References== | ||
Latest revision as of 15:28, March 30, 2023
 | This article is a stub. |
Indoles are a type of molecule. Indole alkaloids include tryptophan, an essential amino acid, serotonin and reserpine.[1]
Function[edit | edit source]
Indole-derivative drugs[edit | edit source]
| Drug | Use |
|---|---|
| Lurasidone | An atypical antipsychotic used to treat schizophrenia, and depression associated with bipolar I disorder |
| Ziprasidone | Schizophrenia, bipolar mania, and agitation in patients with schizophrenia |
| Oxypertine | Unknown |
| Ziprasidone | Schizophrenia, bipolar mania, and agitation in patients with schizophrenia[2] |
ME/CFS[edit | edit source]
See also[edit | edit source]
- Metabolic trap
- Indoleamine-2,3-dioxygenase (IDO)
- Indoleamine-2,3-dioxygenase (IDO2)
- Tryptophan
- Serotonin
Learn more[edit | edit source]
- Indole - PubChem
Notable studies[edit | edit source]
- 2019, Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology[3] (Full text)
References[edit | edit source]
- ↑ Ali, Nasir Shafakat Ali, Vidya Pradhan; Dar, Bashir Ahmad; Pradhan, Vidya; Farooqui, Mazahar (September 30, 2013). "Chemistry and Biology of Indoles and Indazoles: A Mini-Review" (PDF). Mini-Reviews in Medicinal Chemistry. doi:10.2174/1389557511313120009. Retrieved December 18, 2019.
- ↑ https://www.drugbank.ca/categories/DBCAT002255
- ↑ Beloborodova, Natalia V.; Grechko, Andrey V.; Olenin, Andrey Yu (June 26, 2019). "Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology". Metabolomics - New Insights into Biology and Medicine. doi:10.5772/intechopen.87176.
