Glatiramer acetate

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Copaxone or glatopa, and glatiramer, its generic form, is glatiramer acetate (copaxone), an FDA-approved immunomodulator licensed to reduce relapses in patients with multiple sclerosis.[1]

ME/CFS[edit | edit source]

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Dr. Ron Davis on Copaxone in ME/CFS. Inaugural Harvard Symposium, Sep 2019.

Ron Davis of the Open Medicine Foundation reports that when the nanoneedle electrical impedance test on ME/CFS cells was used, Copaxone made the cells respond in the same way as healthy cells did, suggesting it is a potential treatment for ME/CFS.[2]

Notable studies[edit | edit source]

  • 2023, Catalytic Antibodies May Contribute to Demyelination in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[3] - (Full text)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. ↑ "Copaxone: Uses, Dosage, Side Effects". Drugs.com. Retrieved April 30, 2019.
  2. ↑ Davis, Ron (September 2019). "Dr. Ron Davis Presents on ME/CFS Research Activities at Stanford at Inaugural Harvard Symposium". Retrieved September 8, 2019.
  3. ↑ Jensen, Michael Anthony; Dafoe, Miranda Lee; Wilhelmy, Julie; Cervantes, Layla; Okumu, Anna N.; Kipp, Lucas; Nemat-Gorgani, Mohsen; Davis, Ronald Wayne (November 27, 2023). "Catalytic Antibodies May Contribute to Demyelination in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Biochemistry. doi:10.1021/acs.biochem.3c00433. ISSN 1520-4995. PMID 38011893.

immunomodulator An immunomodulator is a substance that affects the functioning of the immune system

nanoneedle A device with microscopic dimensions which measures electrical impedance across a blood cell. According to Ron Davis, the nanoneedle measured increased electrical impedance in the blood cells of 10 ME/CFS patients when stressed with salt, but not in healthy controls. Accordingly, this device has been proposed as a potential diagnostic test to distinguish ME/CFS patients from healthy controls. (Learn more: www.omf.ngo)

antibodies Antibody/immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

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