Gene expression

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Upregulated genes in ME/CFS in one study
Author: Sweetman et al. Current Research Provides Insight into the Biological Basis and Diagnostic Potential for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Diagnostics 2019 9(3) 73. License: CC-BY-4.0

The National Center for Biotechnology Information at the US National Institutes of Health (NIH) defines gene expression as "the phenotypic manifestation of a gene or genes by the processes of genetic transcription and genetic translation."[1] Gene expression takes place in two stages. The first is transcription: the base sequence on DNA is copied to a molecule of mRNA. Next, translation: the mRNA molecule leaves the cell nucleus for the cytoplasm and specifies the particular amino acids that will make up individual proteins in the process of protein synthesis.[1]

Gene expression analysis examines patterns of gene expression in transcription, whether under specific conditions or in certain kinds of cells.[1]

Notable studies[edit | edit source]

  • 2009, A gene signature for post-infectious chronic fatigue syndrome[2]

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References[edit | edit source]