Central nervous system: Difference between revisions
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*[[Sophia Mirza]]'s autopsy showed her spine contained massive infection.<ref name=":0">{{Cite web|url=http://www.investinme.org/Article-050%20Sophia%20Wilson%2001.htm|title=The Story of Sophia and M.E.|last=|first=|date=|website=www.investinme.org|archive-url=|archive-date=|dead-url=|access-date=2018-08-10}}</ref><ref>{{Cite web|url=http://www.sophiaandme.org.uk/neuropathologicalreport.html|title=Neuropathological Report|last=|first=|date=|website=www.sophiaandme.org.uk|archive-url=|archive-date=|dead-url=|access-date=2018-08-10}}</ref> | *[[Sophia Mirza]]'s autopsy showed her spine contained massive infection.<ref name=":0">{{Cite web|url=http://www.investinme.org/Article-050%20Sophia%20Wilson%2001.htm|title=The Story of Sophia and M.E.|last=|first=|date=|website=www.investinme.org|archive-url=|archive-date=|dead-url=|access-date=2018-08-10}}</ref><ref>{{Cite web|url=http://www.sophiaandme.org.uk/neuropathologicalreport.html|title=Neuropathological Report|last=|first=|date=|website=www.sophiaandme.org.uk|archive-url=|archive-date=|dead-url=|access-date=2018-08-10}}</ref> | ||
*[[Lynn Gilderdale]] had ganglionitis which is an infection of [[dorsal root ganglia]] of her spine, typical for a neurological illness.<ref>{{Cite web|url=https://niceguidelines.blogspot.com/2011/04/lynn-gilderdales-autopsy-showed-dorsal.html|title=THE NICEGUIDELINES BLOG: Lynn Gilderdale's autopsy showed 'dorsal root ganglionitis' - infected nerve roots, just like Sophia Mirza's|last=Speedy|first=Dr|date=2011-04-16|website=THE NICEGUIDELINES BLOG|access-date=2018-08-16}}</ref><ref>{{Cite book|url=https://www.amazon.com/One-Last-Goodbye-Sometimes-mothers/dp/0091939143|title=One Last Goodbye: Sometimes only a mother's love can help end the pain|last=Gilderdale|first=Kay|date=2011-04-14|publisher=Ebury Press|year=|isbn=9780091939144|location=|pages=|language=English|Amazon=}}</ref><ref>{{Cite web|url=https://www.talkhealthpartnership.com/forum/viewtopic.php?t=4600|title=talkhealth forums | *[[Lynn Gilderdale]] had ganglionitis which is an infection of [[dorsal root ganglia]] of her spine, typical for a neurological illness.<ref>{{Cite web|url=https://niceguidelines.blogspot.com/2011/04/lynn-gilderdales-autopsy-showed-dorsal.html|title=THE NICEGUIDELINES BLOG: Lynn Gilderdale's autopsy showed 'dorsal root ganglionitis' - infected nerve roots, just like Sophia Mirza's|last=Speedy|first=Dr|date=2011-04-16|website=THE NICEGUIDELINES BLOG|access-date=2018-08-16}}</ref><ref>{{Cite book|url=https://www.amazon.com/One-Last-Goodbye-Sometimes-mothers/dp/0091939143|title=One Last Goodbye: Sometimes only a mother's love can help end the pain|last=Gilderdale|first=Kay|date=2011-04-14|publisher=Ebury Press|year=|isbn=9780091939144|location=|pages=|language=English|Amazon=}}</ref><ref>{{Cite web|url=https://www.talkhealthpartnership.com/forum/viewtopic.php?t=4600|title=talkhealth forums - dorsal root ganglionitis|website=www.talkhealthpartnership.com|access-date=2018-08-16}}</ref> | ||
*[[Merryn Crofts]]'s autopsy showed she had [[ganglionitis]].<ref>{{Cite web|url=https://www.meaction.net/2018/05/19/inquest-rules-merryn-crofts-died-due-to-severe-me/|title=Inquest Rules Merryn Crofts Died Due to Severe ME {{!}} #MEAction|last=Tillman|first=Adriane|date=May 19, 2018|website=www.meaction.net|language=en-US|archive-url=|archive-date=|dead-url=|access-date=2018-08-16}}</ref> | *[[Merryn Crofts]]'s autopsy showed she had [[ganglionitis]].<ref>{{Cite web|url=https://www.meaction.net/2018/05/19/inquest-rules-merryn-crofts-died-due-to-severe-me/|title=Inquest Rules Merryn Crofts Died Due to Severe ME {{!}} #MEAction|last=Tillman|first=Adriane|date=May 19, 2018|website=www.meaction.net|language=en-US|archive-url=|archive-date=|dead-url=|access-date=2018-08-16}}</ref> | ||
Revision as of 21:06, April 5, 2020
The central nervous system (CNS) is made up of the brain and the spinal cord.[2]
The brain and spinal cord have their own immune system.[3] Microglia cells are a part of that immune system.[4]
Injury to the brain or spinal cord, such as those caused by stroke or trauma, result in a considerable weakening of the immune system.[5]
Disease involvement in ME/CFS[edit | edit source]
Autopsy[edit | edit source]
ME/CFS patient autopsies have shown changes to the spinal cord.
- Sophia Mirza's autopsy showed her spine contained massive infection.[6][7]
- Lynn Gilderdale had ganglionitis which is an infection of dorsal root ganglia of her spine, typical for a neurological illness.[8][9][10]
- Merryn Crofts's autopsy showed she had ganglionitis.[11]
Brain imaging[edit | edit source]
Cytokines[edit | edit source]
Cytokines, found in spinal fluid, are increasingly found to be altered in ME/CFS patients and there are several studies by Ian Lipkin and Mady Hornig with the Microbe Discovery Project. See: Cytokine (Chronic Fatigue Syndrome section)
Neuropathological findings[edit | edit source]
Learn more[edit | edit source]
- Central Nervous System[14] Video short
See also[edit | edit source]
- Brain imaging
- Dorsal root ganglia
- Jose Montoya
- Parasympathetic nervous system
- Post-mortem brain studies
- Melvin Ramsay
- Stanford ME/CFS Initiative
References[edit | edit source]
- ↑ "Image: Central nervous system Facts for Kids". kids.kiddle.co. Retrieved September 29, 2018.
- ↑ "Overview of the Nervous System - Brain, Spinal Cord, and Nerve Disorders - MSD Manual Consumer Version". MSD Manual Consumer Version. Retrieved September 29, 2018.
- ↑ "Scientists create new map of brain's immune system". ScienceDaily. February 19, 2019. Retrieved March 31, 2019. Cite has empty unknown parameter:
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(help) - ↑ "Brain immune system is key to recovery from motor neuron degeneration: Results in study point to new approaches for ALS therapy". ScienceDaily. February 20, 2018. Retrieved March 31, 2019. Cite has empty unknown parameter:
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(help) - ↑ "An interconnection between the nervous and immune system: Neuroendocrine reflex triggers infections". ScienceDaily. September 29, 2017. Retrieved March 31, 2019. Cite has empty unknown parameter:
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(help) - ↑ "The Story of Sophia and M.E." www.investinme.org. Retrieved August 10, 2018. Cite has empty unknown parameter:
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(help) - ↑ "Neuropathological Report". www.sophiaandme.org.uk. Retrieved August 10, 2018. Cite has empty unknown parameter:
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(help) - ↑ Speedy, Dr (April 16, 2011). "THE NICEGUIDELINES BLOG: Lynn Gilderdale's autopsy showed 'dorsal root ganglionitis' - infected nerve roots, just like Sophia Mirza's". THE NICEGUIDELINES BLOG. Retrieved August 16, 2018.
- ↑ Gilderdale, Kay (April 14, 2011). One Last Goodbye: Sometimes only a mother's love can help end the pain. Ebury Press. ISBN 9780091939144. Cite has empty unknown parameter:
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(help) - ↑ "talkhealth forums - dorsal root ganglionitis". www.talkhealthpartnership.com. Retrieved August 16, 2018.
- ↑ Tillman, Adriane (May 19, 2018). "Inquest Rules Merryn Crofts Died Due to Severe ME | #MEAction". www.meaction.net. Retrieved August 16, 2018. Cite has empty unknown parameter:
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(help) - ↑ Ferrero, Kimberly; Silver, Mitchell; Cocchetto, Alan; Masliah, Eliezer; Langford, Dianne (April 5, 2017). "CNS findings in chronic fatigue syndrome and a neuropathological case report". Journal of Investigative Medicine: jim–2016–000390. doi:10.1136/jim-2016-000390. ISSN 1081-5589. PMID 28386034.
- ↑ "2-Minute Neuroscience: Divisions of the Nervous System". YouTube. Neuroscientifically Challenged. August 8, 2014. Cite has empty unknown parameter:
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(help) - ↑ "Central Nervous System". blausen.com. November 25, 2015. Retrieved August 16, 2018. Cite has empty unknown parameter:
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(help)