Basal ganglia

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Reduced Activation in Basal Ganglia Structures in CFS compared to Controls for the Win-Lose Contrast.[1]
Source: Miller et al. (2014). PLoS ONE 9(5): e98156. doi:10.1371/journal.pone.0098156

Basal ganglia are a set of structures in the brain regulated by dopamine that play a role in action selection, voluntary movements and executive function, as well as perception of effort.

ME/CFS[edit | edit source]

A small study of chronic fatigue syndrome patients found increased choline in the basal ganglia.[2] Increased choline can be a sign of immune activation or increased cell membrane turnover.

Notable studies[edit | edit source]

  • 2014, Decreased Basal Ganglia Activation in Subjects with Chronic Fatigue Syndrome: Association with Symptoms of Fatigue[1] (Full text)
  • 2003, Proton magnetic resonance spectroscopy of basal ganglia in chronic fatigue syndrome[2] (Full text)

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References[edit | edit source]