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Bifidobacteria are gram-positive, anaerobic bacteria that are ubiquitous in a healthy gastrointestinal tract. They are protective against intestinal permeability.

Decreased populations of bifidiobacteria have been associated with vitamin K deficiency,[1] atopic diseases,[2]irritable bowel syndrome,[3] and autism.[4][5]

Chronic fatigue syndrome[edit | edit source]

Bifidobacteria have been shown to be reduced in CFS patients.[6]

One study found that 6-8 weeks of Bifidobacterium infantis supplementation reduced C-reactive protein, TNF-alpha and IL-6 levels in CFS patients.[7] Another found that B. infantis boosted serotonin levels in the brain.[citation needed]

FUT2[edit | edit source]

Fucosyltransferase 2 enzyme (FUT2) is an enzyme related to intestinal dysbiosis. People who are genetic non-secretors of FUT2 have reduced diversity, richness, and abundance of bifidobacteria.[8]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. Benno et al., 1985
  2. (Kalliomakiet al., 2001)
  3. (Kerckhoffs et al., 2009; Rajilić-Stojanović et al., 2011)
  4. (Wang et al., 2011a)
  6. Chronic fatigue syndrome: lactic acid bacteria may be of therapeutic value
  7. Groeger, David; O'Mahony, Liam; Murphy, Eileen F.; Bourke, John F.; Dinan, Timothy G.; Kiely, Barry; Shanahan, Fergus; Quigley, Eamonn M. M. (August 2013), "Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut", Gut Microbes, 4 (4): 325–339, doi:10.4161/gmic.25487, ISSN 1949-0984, PMC 3744517Freely accessible, PMID 23842110  .
  8. Secretor Genotype (FUT2 gene) Is Strongly Associated with the Composition of Bifidobacteria in the Human Intestine

chronic fatigue syndrome (CFS) - A controversial term, invented by the U.S. Centers for Disease Control, that generally refers to a collection of symptoms as “fatigue”. There have been multiple attempts to come up with a set of diagnostic criteria to define this term, but few of those diagnostic criteria are currently in use. Previous attempts to define this term include the Fukuda criteria and the Oxford criteria. Some view the term as a useful diagnostic category for people with long-term fatigue of unexplained origin. Others view the term as a derogatory term borne out of animus towards patients. Some view the term as a synonym of myalgic encephalomyelitis, while others view myalgic encephalomyelitis as a distinct disease.

enzyme - a substance produced by a living organism which acts as a catalyst to bring about a specific biochemical reaction.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.