Denis Wakefield

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Denis Wakefield is an immunologist and professor at the University of New South Wales (UNSW) Sydney's School of Medical Sciences.[1]

Education[edit | edit source]

Wakefield attended UNSW, graduating with First Class Honours and winning the University Medal for Medicine. He earned dual specialist qualifications in internal medicine (FRACP) and pathology (FRCPA) (immunology).[1]

Career[edit | edit source]

Wakefield was Head of the School of Pathology for ten years before becoming foundation professor of the School of Medical Sciences at the UNSW.[1] He is Director of the Centre for Immunology and Head of Immunopathology with the South Eastern Area Health Service.[1] In 2007, he was appointed Associate Dean for Research and Director of Medical Research.[1]

Notable studies[edit | edit source]

  • 1997, Cognitive deficits in patients suffering from chronic fatigue syndrome, acute infective illness or depression[2]
  • 1998, Chronic fatigue syndrome: An immunological perspective.[3]
  • 1998, Mast cell activation and migration to lymph nodes during induction of an immune response in mice[4]
  • 2000, A randomized, double-blind, placebo-controlled trial of moclobemide in patients with chronic fatigue syndrome.[5]
  • 2001, What is chronic fatigue syndrome? Heterogeneity within an international multicentre study.[6]
  • 2006, Prolonged Illness after Infectious Mononucleosis Is Associated with Altered Immunity but Not with Increased Viral Load.[7]
  • 2006, Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study.[8]
  • 2007, Gene expression correlates of postinfective fatigue syndrome after infectious mononucleosis.[9]
  • 2007, Postinfective fatigue syndrome is not associated with altered cytokine production.[10]
  • 2016, The natural history of acute Q fever: A prospective Australian cohort[11]

References[edit | edit source]

  1. 1.01.11.21.31.4 "Professor Denis Wakefield". research.unsw.edu.au. Retrieved Jan 30, 2019. 
  2. Vollmer-Conna, Ute; Wakefield, Denis; Lloyd, Andrew; Hickie, Ian; Lemon, J.; Bird, K. D.; Westbrook, R. F. (Oct 1997). "Cognitive deficits in patients suffering from chronic fatigue syndrome, acute infective illness or depression". The British Journal of Psychiatry: The Journal of Mental Science. 171: 377–381. ISSN 0007-1250. PMID 9373430. 
  3. Vollmer-Conna, Ute; Lloyd, Andrew; Hickie, Ian; Wakefield, Denis (Aug 1998). "Chronic fatigue syndrome: an immunological perspective". The Australian and New Zealand Journal of Psychiatry. 32 (4): 523–527. doi:10.3109/00048679809068326. ISSN 0004-8674. PMID 9711366. 
  4. Wang, H. W.; Tedla, N.; Lloyd, A. R.; Wakefield, D.; McNeil, P. H. (Oct 15, 1998). "Mast cell activation and migration to lymph nodes during induction of an immune response in mice". The Journal of Clinical Investigation. 102 (8): 1617–1626. doi:10.1172/JCI3704. ISSN 0021-9738. PMID 9788976. 
  5. Lloyd, Andrew R.; Bennett, Barbara K.; Wright, J. Murray; Wilson, Andrew J.; Hickie, Ian B. (Sep 30, 2000). "A Randomized, Double-Blind, Placebo-Controlled Trial of Moclobemide in Patients With Chronic Fatigue Syndrome". The Journal of Clinical Psychiatry. 61 (9): 643–648. ISSN 0160-6689. 
  6. Wilson, A.; Hickie, Ian; Hadzi-Pavlovic, Dusan; Wakefield, Denis; Parker, G.; Straus, S. E.; Dale, J.; McCluskey, D.; Hinds, G. (Aug 2001). "What is chronic fatigue syndrome? Heterogeneity within an international multicentre study". The Australian and New Zealand Journal of Psychiatry. 35 (4): 520–527. doi:10.1046/j.1440-1614.2001.00888.x. ISSN 0004-8674. PMID 11531735. 
  7. Lloyd, Andrew; Khanna, Rajiv; Ffrench, Rosemary; Hickie, Ian; Wakefield, Denis; Fazou, Chrysa; Burrows, Jacqueline; Bharadwaj, Mandvi; Cameron, Barbara (Mar 1, 2006). "Prolonged Illness after Infectious Mononucleosis Is Associated with Altered Immunity but Not with Increased Viral Load". The Journal of Infectious Diseases. 193 (5): 664–671. doi:10.1086/500248. ISSN 0022-1899. 
  8. Hickie, Ian; Davenport, Tracey; Wakefield, Denis; Vollmer-Conna, Ute; Cameron, Barbara; Vernon, Suzanne D; Reeves, William C; Lloyd, Andrew (Sep 16, 2006). "Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study". BMJ. 333 (7568): 575–. doi:10.1136/bmj.38933.585764.ae. PMC 1569956Freely accessible. PMID 16950834. 
  9. Cameron, Barbara; Galbraith, Sally; Zhang, Yun; Davenport, Tracey; Vollmer-Conna, Ute; Wakefield, Denis; Hickie, Ian; Dunsmuir, William; Whistler, Toni (Jul 1, 2007). "Gene expression correlates of postinfective fatigue syndrome after infectious mononucleosis". The Journal of Infectious Diseases. 196 (1): 56–66. doi:10.1086/518614. ISSN 0022-1899. PMID 17538884. 
  10. Vollmer-Conna, Uté; Cameron, Barbara; Hadzi-Pavlovic, Dusan; Singletary, Kristi; Davenport, Tracey; Vernon, Suzanne; Reeves, William C.; Hickie, Ian; Wakefield, Denis (Sep 15, 2007). "Postinfective fatigue syndrome is not associated with altered cytokine production". Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America. 45 (6): 732–735. doi:10.1086/520990. ISSN 1537-6591. PMID 17712757. 
  11. Hopper, B.; Cameron, B.; Li, H.; Graves, S.; Stenos, J.; Hickie, I.; Wakefield, D.; Vollmer-Conna, U.; Lloyd, A.R. (Oct 2016). "The natural history of acute Q fever: a prospective Australian cohort". QJM. 109 (10): 661–668. doi:10.1093/qjmed/hcw041. ISSN 1460-2725. 

chronic fatigue syndrome (CFS) - A controversial term, invented by the U.S. Centers for Disease Control, that generally refers to a collection of symptoms as “fatigue”. There have been multiple attempts to come up with a set of diagnostic criteria to define this term, but few of those diagnostic criteria are currently in use. Previous attempts to define this term include the Fukuda criteria and the Oxford criteria. Some view the term as a useful diagnostic category for people with long-term fatigue of unexplained origin. Others view the term as a derogatory term borne out of animus towards patients. Some view the term as a synonym of myalgic encephalomyelitis, while others view myalgic encephalomyelitis as a distinct disease.

chronic fatigue syndrome (CFS) - A controversial term, invented by the U.S. Centers for Disease Control, that generally refers to a collection of symptoms as “fatigue”. There have been multiple attempts to come up with a set of diagnostic criteria to define this term, but few of those diagnostic criteria are currently in use. Previous attempts to define this term include the Fukuda criteria and the Oxford criteria. Some view the term as a useful diagnostic category for people with long-term fatigue of unexplained origin. Others view the term as a derogatory term borne out of animus towards patients. Some view the term as a synonym of myalgic encephalomyelitis, while others view myalgic encephalomyelitis as a distinct disease.

BMJ - The BMJ (previously the British Medical Journal) is a weekly peer-reviewed medical journal.

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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.