Methylene blue

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Methylene blue or methylthioninium chloride (MB) is a medication and dye that also functions as an antioxidant.[1][2][3]

Theory[edit | edit source]

Methylene blue is claimed to lead to better oxygenation of tissues, mitochondrial protection and recovery, improved memory and cognition. It is used sublingually by some ME/CFS patients.

Evidence[edit | edit source]

No clinical trials of methylene blue have been conducted in ME/CFS patients.

Clinicians[edit | edit source]

Risks and safety[edit | edit source]

Serotonin syndrome and a number of other serious side effects may result from the use of methylene blue. It also turns skin and mucosa a bluish color and urine a greenish blue color.[2][4]

Costs and availability[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. "Methylene blue (CHEBI:6872)". Chemical Entities of Biological Interest. Retrieved November 29, 2020.
  2. 2.0 2.1 American Society of Health-System Pharmacists. "Methylene Blue Monograph for Professionals". Retrieved November 29, 2020.
  3. "Methylene blue". Retrieved November 29, 2020.
  4. Ginimuge, Prashant R.; Jyothi, S.D. (2010). "Methylene Blue: Revisited". Journal of Anaesthesiology, Clinical Pharmacology. 26 (4): 517–520. ISSN 0970-9185. PMC 3087269. PMID 21547182.