Ronald Glaser

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M. Ronald Glaser, Ph.D, (d. April 3, 2019)[1] was a professor in the Department of Cancer Biology and Genetics and Director of the Institute for Behavioral Medicine Research at the College of Medicine, The Ohio State University, Columbus, Ohio. His main research interests were tumor virology/stress and immunology.[2]

Dr. Glaser advocated that a possible subset of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) could be from viral reactivation following a stressful event.[3] In 2012, Dr Glaser and his team announced work on a possible diagnostic biomarker for CFS that involves the detection of EBV-encoded DNA polymerase and EBV-encoded dUTPase, two proteins that are produced early in the process of Epstein-Barr virus reactivation.[4]

Chronic Fatigue Syndrome Advisory Committee[edit | edit source]

Dr. Glaser served as a voting member of the Chronic Fatigue Syndrome Advisory Committee from 04/01/07 to 04/01/11.[5][6]

2001 CDC Case Definition Workshop[edit | edit source]

In 2001, the CDC held a three-day workshop on Issues Related to the Chronic Fatigue Syndrome (CFS) Research Case Definition. Dr Glaser was one of the invited participants. During the workshop, Dr Glaser gave the presentation: "Immune Modulation by Latent Herpesvirus Proteins."[7]

Notable studies[edit | edit source]

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. "Ronald Glaser - View Obituary & Service Information". Ronald Glaser Obituary. Retrieved Apr 6, 2019. 
  2. https://medicine.osu.edu/cancer-biology-genetics/directory/molecular-virology/glaser-m-ronald-phd/Pages/index.aspx
  3. http://www.ei-resource.org/columns/phoenix-rising/chronic-fatigue-syndrome-and-the-pathophysiology-of-epstein-barr-virus-ebv-infection
  4. http://researchnews.osu.edu/archive/chronfatigue.htm
  5. HHS.gov (2009), May 27 & 28, 2009 CFSAC Meeting (PDF) (Roster) 
  6. HHS.gov (2010), October 12 & 13, 2010 CFSAC Meeting (PDF) (Roster) 
  7. https://www.cdc.gov/cfs/meetings/case_def_05_2001.html
  8. Glaser, Ronald; Rice, John; Speicher, Carl E.; Stout, Julie C.; Kiecolt-Glaser, Janice K. (Oct 1986), "Stress depresses interferon production by leukocytes concomitant with a decrease in natural killer cell activity.", Behavioral Neuroscience, 100(5): 675-678, doi:10.1037/0735-7044.100.5.675 
  9. Glaser, R; Kiecolt-Glaser, JK (1998), "Stress-associated immune modulation: relevance to viral infections and chronic fatigue syndrome.", The American Journal of Medicine, 105(3A): 35S-42S, PMID 9790480 
  10. Glaser, R.; Padgett, D.A.; Litsky, M.L.; Baiocchi, R.A.; Yang, E.V.; Chen, M.; Yeh, P-E.; Klimas, N.G.; Marshall, G.D.; Whiteside, T.; Herberman, R.; Kiecolt-Glaser, J.K.; Williams, M.V. (2005), "Stress-associated changes in the steady state expression of latent Epstein-Barr Virus: Implications for Chronic Fatigue Syndrome and Cancer", Brain, Behavior and Immunity, 19 (2): 91-103, doi:10.1016/j.bbi.2004.09.001, PMID 15664781 
  11. Lerner, AM; Ariza, ME; Williams, M; Jason, L; Beqaj, S; Fitzgerald, JT; Lemeshow, S; Glaser, R (2012), "Antibody to Epstein-Barr Virus Deoxyuridine Triphosphate Nucleotidohydrolase and Deoxyribonucleotide Polymerase in a Chronic Fatigue Syndrome Subset", PLoS ONE, 7 (11): e47891, doi:10.1371/journal.pone.0047891 

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

Chronic Fatigue Syndrome Advisory Committee (CFSAC) - (sometimes pronounced SIF-SACK) A US government advisory council that met twice per year, covering current topics related to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Meetings usually lasted for two days and the results were presented to the Secretary of Health and Human Services (HHS). After 15 years, on September 5, 2018, CFSAC's charter was not renewed by the Department of HHS, effectively dissolving the committee without notice or warning.

Centers for Disease Control and Prevention (CDC) - The Centers for Disease Control and Prevention is a U.S. government agency dedicated to epidemiology and public health. It operates under the auspices of the Department of Health and Human Services.

chronic fatigue syndrome (CFS) - A fatigue-based illness. The term CFS was invented invented by the U.S. Centers for Disease Control as an replacement for myalgic encephalomyelitis (ME). Some view CFS as a neurological disease, others use the term for any unexplained long-term fatigue. Sometimes used as a the term as a synonym of myalgic encephalomyelitis, despite the different diagnostic criteria.

antibody - Antibodies or immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.

chronic fatigue syndrome (CFS) - A fatigue-based illness. The term CFS was invented invented by the U.S. Centers for Disease Control as an replacement for myalgic encephalomyelitis (ME). Some view CFS as a neurological disease, others use the term for any unexplained long-term fatigue. Sometimes used as a the term as a synonym of myalgic encephalomyelitis, despite the different diagnostic criteria.

myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

The information provided at this site is not intended to diagnose or treat any illness.
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