Neuroimmune disease (disorder, syndrome, or condition) is an umbrella term for a group of certain diseases involving dysfunction of both the immune system and the nervous system. It is not an official classification of disease, but it used to refer to neurological diseases which are also recognized as immune or autoimmune diseases.
Neuroimmune disorders[edit | edit source]
Disorders Commonly Found In Adults:
- Systemic lupus erythematosus
- Multiple Sclerosis
- Amyotrophic lateral sclerosis (ALS or Motor Neuron Disease)
- Guillain-Barré syndrome
- Myasthenia gravis
- Neuromyelitis optica (NMO)
Potential neuroimmune disorders[edit | edit source]
These disorders have considerable evidence of a neuroimmune disease process, but are not widely accepted as neuroimmune conditions.
Diseases which may have neuroimmune symptoms[edit | edit source]
A wide range of diseases have been proposed as neuroimmune diseases, but evidence is limited and most of those conditions are not recognized as having prominent immune symptoms or are not currently classed as neurological diseases.
Immune symptoms in ME/CFS[edit | edit source]
- recurrent sore throat
- recurrent flu-like symptoms
See also[edit | edit source]
- Neuroimmune model
- National Centre for Neuroimmunology and Emerging Diseases - Australia
- Institute for Neuro-Immune Medicine (United States)
Learn more[edit | edit source]
- Institute for Neuro-Immune Medicine
- National Centre for Neuroimmunology and Emerging Diseases
- Neuroimmune Syndromes (NeuroSensory Centers of America)
- Immune system diseases - National Institute of Health
References[edit | edit source]
- NSU | Institute for Neuro Immune Medicine. "Institute for Neuro-Immune Medicine Clinic". NSU. Retrieved May 10, 2019.
- World Health Organization. "ICD-10 Version:2016 | Neurological diseases". icd.who.int. Retrieved May 9, 2019.
- "Autoimmune Diseases". National Institute of Environmental Health Sciences. Retrieved May 10, 2019.
- "Immune System Diseases | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Retrieved May 10, 2019.
- Tumani, Hayrettin; Otto, Markus; Ludolph, Albert C.; Kassubek, Jan; Brettschneider, Johannes; Junker, Andreas; Abdelhak, Ahmed (Aug 2015). "Brain-Specific Cytoskeletal Damage Markers in Cerebrospinal Fluid: Is There a Common Pattern between Amyotrophic Lateral Sclerosis and Primary Progressive Multiple Sclerosis?". International Journal of Molecular Sciences. 16 (8): 17565–17588. doi:10.3390/ijms160817565.
- Uchitel, Osvaldo Daniel; Gonzalez, Laura Elisabeth; Pagani, Mario Rafael (2011). "Autoimmunity in Amyotrophic Lateral Sclerosis: Past and Present". Neurology Research International. PMID 21826267. Retrieved May 10, 2019.
- Jin, Tao; Zhu, Jie; Jiang, Xinmei; Cheng, Yun; Zhang, Hongliang; Fan, Xueli (2016). "Double Roles of Macrophages in Human Neuroimmune Diseases and Their Animal Models". Mediators of Inflammation. Retrieved May 10, 2019.
- "Cornell Center for Enervating NeuroImmune Disease". Retrieved Mar 30, 2019.
- "What is Myalgic Encephalomyelitis (ME)?". #MEAction. Retrieved Mar 30, 2019.
- Georgopoulos, Apostolos P.; James, Lisa M.; Carpenter, Adam F.; Engdahl, Brian E.; Leuthold, Arthur C.; Lewis, Scott M. (Oct 1, 2017). "Gulf War illness (GWI) as a neuroimmune disease". Experimental Brain Research. 235 (10): 3217–3225. doi:10.1007/s00221-017-5050-0. ISSN 1432-1106.
- "National Centre for Neuroimmunology and Emerging Diseases". www.griffith.edu.au. Retrieved May 11, 2019.
Myalgic encephalomyelitis or chronic fatigue syndrome, often used when both illnesses are considered the same.