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Modafinil
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
 | This article is a stub. |
Modafinil is a non-stimulant medication used to improve wakefulness in adult patients with excessive sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work disorder (SWD).[1] In the United States, it is marketed with the name Provigil.
Evidence[edit | edit source]
Modafinal is a suggested treatment for fatigue (increased energy and alertness) in the Canadian Consensus Criteria, with 100mg suggested in the morning and adding another 100mg at noon.[2]
Notable studies[edit | edit source]
- 2021, Recovery from Refractory Chronic Fatigue Syndrome with CBT and Modafinil[3]
- 2000, Effect of Modafinil on Fatigue Associated with Neurological Illnesses[4]
References[edit | edit source]
- ↑ "Medication Guide" (PDF). U.S. Food & Drug Administration. Retrieved June 15, 2019.
- ↑ Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, AC Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 7–115, doi:10.1300/J092v11n01_02
- ↑ Garg, Himanshu; Douglas, Maggie; Turkington, Gordon Douglas; Turkington, Douglas (March 22, 2021). "Recovery from refractory chronic fatigue syndrome with CBT and modafinil". BMJ Case Reports. 14 (3): e240283. doi:10.1136/bcr-2020-240283. ISSN 1757-790X. PMC 7986944. PMID 33753384.
- ↑ Cochran, John W. (2000). "Effect of Modafinil on Fatigue Associated with Neurological Illnesses". Journal of Chronic Fatigue Syndrome. 8 (2): 65–70. doi:10.1300/J092v08n02_06. ISSN 1057-3321.
