Jesús Castro-Marrero

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Source:Vall d'Hebron Research Institute (VHIR)

Jesús Castro-Marrero, PhD, (also known as Jesus Castro) works at Cornell ME/CFS Collaborative Research Center, New York, US. His research focuses on Extracellular Vesicles/Exosomes biology and decoding differences in the mRNA and miRNA expression cargo from Extracellular Vesicles (EVs) and blood immune cells (peripheral blood mononuclear cells) before and after a 24 hour CPET challenge in a gender-specific manner in individuals with ME/CFS.

Previously, he was a Senior Research Associate in Biochemistry and Molecular Biology at the Vall d’Hebron University Hospital Research Institute (VHIR), Barcelona, Spain.[1]

EUROMENE[edit | edit source]

Dr. Castro-Marrero is a Working Group Leader on Epidemiology of ME/CFS across Europe on behalf of the EUROMENE, a European Union not-for-profit research organization committed to tackling the cause and treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.[2]

Education[edit | edit source]

  • 1987 - B.S. in Biochemistry, School of Biological Sciences, University of Havana, Cuba
  • 1999 - Ph.D. in Biochemistry and Molecular Biology, Valladolid University School of Medicine, Spain

Notable studies[edit | edit source]

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. "Vall d'Hebron Research Institute (VHIR)". en.vhir.org. Retrieved Jul 15, 2019. 
  2. http://www.cost.eu/COST_Actions/ca/CA15111?management
  3. Curriu, Marta; Carrillo, Jorge; Massanella, Marta; Rigau, Josepa; Alegre, José; Puig, Jordi; Garcia-Quintana, Ana M; Castro-Marrero, Jesús; Negredo, Eugènia; Clotet, Bonaventura; Cabrera, Cecilia; Blanco, Julià (2013), "Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome", Journal of Translational Medicine, 11 (68), doi:10.1186/1479-5876-11-68 
  4. Castro-Marrero, J.; Cordero, M.D.; Sáez-Francas, N.; Jimenez-Gutierrez, C.; Aguilar-Montilla, F.J.; Aliste, L.; Alegre-Martin, J. (2013), "Could mitochondrial dysfunction be a differentiating marker between chronic fatigue syndrome and fibromyalgia?", Antioxidants & Redox Signaling, 19 (15): 1855-1860, doi:10.1089/ars.2013.5346, PMID 23600892 
  5. Faro, M.; Sáez-Francàs, N.; Castro-Marrero, J.; Aliste, L.; Collado, A.; Alegre, J. (2014), "Impact of the fibromyalgia in the chronic fatigue syndrome", Medicina Clinica (Barc), 142 (12): 519-525, doi:10.1016/j.medcli.2013.06.030, PMID 24387955 
  6. Castro-Marrero, J.; Cordero, M.D.; Segundo, M.J.; Sáez-Francàs, N.; Calvo, N.; Román-Malo, L.; Aliste, L.; Fernández de Sevilla, T.; Alegre, J. (2015), "Does Oral Coenzyme Q10 Plus NADH Supplementation Improve Fatigue and Biochemical Parameters in Chronic Fatigue Syndrome?", Antioxidants & Redox Signaling, 22 (8): 679–685, doi:10.1089/ars.2014.6181, PMID 25386668 
  7. Calvo, N.; Sáez-Francas, N.; Valero, S.; Castro-Marrero, J.; Alegre, J.; Casas, M. (2015), "Diagnostic concordance between categorical and dimensional instrument to assess personality in chronic fatigue syndrome: PDQ-4+ and TCI-R", European Journal of Psychological Assessment, 33: 158-165, doi:10.1027/1015-5759/a000281 
  8. Sáez-Francàs, Naia; Calvo, Natalia; Alegre, José; Castro-Marrero, Jesús; Casas, Miguel (2015), "Childhood trauma in Chronic Fatigue Syndrome: focus on personality disorders and psychopathology", Comprehensive Psychiatry, 62: 13-19, doi:10.1016/j.comppsych.2015.06.010 
  9. Faro, Mónica; Sáez-Francàs, Naia; Castro-Marrero, Jesús; Aliste, Luisa; Fernández de Sevilla, Tomás; Alegre, Jose (2015), "Gender Differences in Chronic Fatigue Syndrome", Reumatologia clinica, 12 (2), doi:10.1016/j.reuma.2015.05.007 
  10. Scheibenbogen, Carmen; Freitag, Helma; Blanco, Julià; Capelli, Enrica; Lacerda, Eliana; Authier, Jerome; Meeus, Mira; Castro Marrero, Jesus; Nora-Krukle, Zaiga; Oltra, Elisa; Strand, Elin Bolle; Shikova, Evelina; Sekulic, Slobodan; Murovska, Modra (Jul 26, 2017). "The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE". Journal of Translational Medicine. 15 (1). doi:10.1186/s12967-017-1263-z. ISSN 1479-5876. PMC 5530475Freely accessible. PMID 28747192. 
  11. Castro-Marrero, J. (2017), "Treatment and management of chronic fatigue syndrome/myalgic encephalomyelitis: all roads lead to Rome", British Journal of Pharmacology, 174 (5): 345–369, doi:10.1111/bph.13702, PMID 28052319 
  12. Castro-Marrero, J.; Faro, M.; Aliste, L.; Sáez-Francàs, N.; Calvo, N.; Martínez-Martínez, A.; de Sevilla, T.F.; Alegre, J. (2017), "Comorbidity in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Nationwide Population-Based Cohort Study", Psychosomatics, 58 (5): 533 - 543, doi:10.1016/j.psym.2017.04.010 
  13. Cambras, T.; Castro-Marrero, J.; Zaragoza, MC.; Díez-Noguera, A.; Alegre, J. (2018), "Circadian rhythm abnormalities and autonomic dysfunction in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis", PLoS ONE, 13 (6): e0198106, doi:10.1371/journal.pone.0198106 
  14. Castro-Marrero, Jesús; Zaragozá, Maria Cleofé; González-Garcia, Sergio; Aliste, Luisa; Sáez-Francàs, Naia; Romero, Odile; Ferré, Alex; Fernández de Sevilla, Tomás; Alegre, José (2018), "Poor self-reported sleep quality and health-related quality of life in patients with chronic fatigue syndrome/myalgic encephalomyelitis", J Sleep Res: e12703, doi:10.1111/jsr.12703, PMID 29770505 
  15. Sotzny, Franziska; Blanco, Julià; Capelli, Enrica; Castro-Marrero, Jesús; Steiner, Sophie; Murovska, Modra; Scheibenbogen, Carmen (2018), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome – Evidence for an autoimmune disease", Autoimmunity Reviews, doi:10.1016/j.autrev.2018.01.009 
  16. Castro-Marrero, Jesús; Serrano-Pertierra, Esther; Oliveira-Rodríguez, Myriam; Zaragozá, Maria Cleofé; Martínez-Martínez, Alba; Blanco-López, María del Carmen; Alegre, José (2018), "Circulating extracellular vesicles as potential biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis: an exploratory pilot study", Journal of Extracellular Vesicles, 7 (1), doi:10.1080/20013078.2018.1453730 
  17. Calvo, Natalia; Pueyo, Natalia; Gutiérrez, Fernando; Ferrer, Marc; Castro-Marrero, Jesús; Alegre, José; Casas, Miquel; Ramos Quiroga, Josep-Antoni; Sáez-Francàs, Naia (Jul 2018). "Dimensional Personality Assessment among a Chronic Fatigue Syndrome (CFS) sample with Personality Inventory for DSM-5 (PID-5)". Actas Espanolas De Psiquiatria. 46 (4): 125–132. ISSN 1578-2735. PMID 30079926. 
  18. Estévez-López, Fernando; Castro-Marrero, Jesus; Wang, Xia; Bakken, Inger Johanne; Ivanovs, Andrejs; Nacul, Luis; Sepúlveda, Nuno; Strand, Elin B.; Pheby, Derek; Alegre, José; Scheibenbogen, Carmen; Shikova, Evelina; Lorusso, Lorenzo; Capelli, Enrica; Sekulic, Slobodan; Lacerda, Eliana; Murovska, Modra (Sep 1, 2018). "Prevalence and incidence of myalgic encephalomyelitis/chronic fatigue syndrome in Europe—the Euro-epiME study from the European network EUROMENE: a protocol for a systematic review". BMJ Open. 8 (9): e020817. doi:10.1136/bmjopen-2017-020817. ISSN 2044-6055. PMID 30181183. 
  19. Castro-Marrero, Jesús; Zaragozá, Maria Cleofé; Domingo, Joan Carles; Martinez-Martinez, Alba; Alegre, José; von Schacky, Clemens (Dec 2018). "Low omega-3 index and polyunsaturated fatty acid status in patients with chronic fatigue syndrome/myalgic encephalomyelitis". Prostaglandins, Leukotrienes and Essential Fatty Acids. 139: 20–24. doi:10.1016/j.plefa.2018.11.006. ISSN 0952-3278. 
  20. Castro-Marrero, Jesús; Faro, Mónica; Zaragozá, María Cleofé; Aliste, Luisa; de Sevilla, Tomás Fernández; Alegre, José (Dec 2019). "Unemployment and work disability in individuals with chronic fatigue syndrome/myalgic encephalomyelitis: a community-based cross-sectional study from Spain". BMC Public Health. 19 (1). doi:10.1186/s12889-019-7225-z. ISSN 1471-2458. PMC 6599355Freely accessible. PMID 31253111. 

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.