Susan Levine

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Susan M. Levine, MD, works with ME/CFS patients at her medical office in New York City, New York, United States.

Dr. Levine is a clinician for the Center for Enervating NeuroImmune Disease at Cornell University, New York and is a member of the Working Group which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.[1]

Education[edit | edit source]

  • Albert Einstein School of Medicine, graduated in 1981
  • residency in Internal Medicine at Montefiore Hospital, Bronx, NYC
  • fellowship in Infectious Diseases at Memorial Sloan Kettering Cancer Center, NYC
  • fellowship in Allergy and Immunology at Mt. Sinai Hospital, NYC[2]

Committees[edit | edit source]

IOM Committee on Diagnostic Criteria for ME/CFS[edit | edit source]

Dr Levine was a reviewer for the 2015 report produced by the Institute of Medicine's Committee on Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.[3]

Chronic Fatigue Syndrome Advisory Committee[edit | edit source]

She served on the Chronic Fatigue Syndrome Advisory Committee (CFSAC) which advises the U.S. Department of Health and Human Services from 10 May 2010 to 10 May 2017, her term having been extended twice. From 2014 to 2017 she served as the committee chair.[4][5][6]

ME/CFS Common Data Element (CDE) Project[edit | edit source]

Member of the Sleep Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke and the Centers for Disease Control and Prevention.[7]

Notable studies and articles[edit | edit source]

Clinic location[edit | edit source]

115 E 72nd St.,
New York, NY 10021
Tel: (212) 472-4816

Talks and interviews[edit | edit source]

Part 1 - Written questions and answers to Dr. Levine's webinar
Part 2 - Written questions and answers to Dr. Levine's webinar

Open Letter to The Lancet[edit | edit source]

Two open letters to the editor of The Lancet urged the editor to commission a fully independent review of the PACE trial, which the journal had published in 2011. In 2016, Dr. Levine, along with 41 colleagues in the ME/CFS field, signed the second letter.

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. "OMF grants $1.2M to Ramp Up Collaborative Research Center at Stanford University". Retrieved January 21, 2019.
  2. Chronic Fatigue Initiative. "Lead researchers | Susan M. Levine". Retrieved January 21, 2019.
  3. IOM (Institute of Medicine) (2015). Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness. Washington, DC: The National Academies Press.
  7. "Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster". NIH. Retrieved October 11, 2019.
  8. Susan Levine. (1999). Borna Disease Virus Proteins in Patients with CFS. Journal of Chronic Fatigue Syndrome, Vol. 5, Iss. 3-4, pp. 199-206.
  9. Levine, Susan; Eastman, Helen; Ablashi, Dharam V. (2001), "Prevalence of IgM and IgG Antibody to HHV-6 and HHV-8 and Results of Plasma PCR to HHV-6 and HHV-7 in a Group of CFS Patients and Healthy Donors", Journal of Chronic Fatigue Syndrome, 9 (1–2): 31–40, doi:10.1300/J092v09n01_04
  10. Levine, Susan (2001), "Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects: Human Herpes Virus-6 and 8; Chlamydia Species; Mycoplasma Species; EBV; CMV; and Coxsackievirus", Journal of Chronic Fatigue Syndrome, 9 (1–2): 41-51, doi:10.1300/J092v09n01_05
  11. {{Citation | last1 = Gerrity | first1 = T.R. | authorlink1 = | last2 = Papanicolaou | first2 = D.A. | authorlink2 = | last3 = Amsterdam | first3 = J.D. | authorlink3 = | last4 = Bingham | first4 = S. | authorlink4 = | last5 = Grossman | first5 = A. | authorlink5 = | last6 = Hedrick | first6 = T. | authorlink6 = | last7 = Herberman | first7 = R.B. | authorlink7 = | last8 = Krueger | first8 = G. | authorlink8 = | last9 = Levine | first9 = S. | authorlink9 = Susan Levine | last10 = Mohagheghpour | first10 = N. | authorlink10 = Nahid Mohagheghpour | last11 = Moore | first11 = R.C. | authorlink11 = | last12 = Oleske | first12 = J.M. | authorlink12 = James Oleske | last13 = Snell | first13 = C.R. | authorlink13 = Christopher Snell | last14 = CFIDS Association of America | title = Immunologic Aspects of Chronic Fatigue Syndrome: Report on a Research Symposium Convened by The CFIDS Association of America and Co-Sponsored by the US Centers for Disease Control and Prevention and the National Institutes of Health | journal = Neuroimmunomodulation | volume = 11 | issue = | pages = 351–357 | date = 2004 | pmid = 15467349 | doi = 10.1159/000080144
  12. Alter, Harvey J.; Mikovits, Judy A.; Switzer, William M.; Ruscetti, Francis W.; Lo, Shyh-Ching; Klimas, Nancy; Komaroff, Anthony L.; Montoya, Jose G.; Bateman, Lucinda; Levine, Susan; Peterson, Daniel; Levin, Bruce; Hanson, Maureen R.; Genfi, Afia; Bhat, Meera; Zheng, HaoQiang; Wang, Richard; Li, Bingjie; Hung, Guo-Chiuan; Lee, Li Ling; Sameroff, Stephen; Heneine, Walid; Coffin, John; Hornig, Mady; Lipkin, W. Ian (2012), "A Multicenter Blinded Analysis Indicates No Association between Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and either Xenotropic Murine Leukemia Virus-Related Virus or Polytropic Murine Leukemia Virus", mBio, 3 (5): e00266–12, doi:10.1128/mBio.00266-12
  13. Klimas, N.G.; Ironson, G.; Carter, A.; Balbin, E.; Bateman, L.; Felsenstein, D.; Levine, S.; Peterson, D.; Chiu, K.; Allen, A.; Cunningham, K.; Gottschalk, C.G.; Fletcher, M; Hornig, M.; Canning, C.; Komaroff, A.L. (2015), "Findings from a clinical and laboratory database developed for discovery of pathogenic mechanisms in myalgic encephalomyelitis/chronic fatigue syndrome", Fatigue: Biomedicine, Health & Behavior, 3 (2): 75-96, doi:10.1080/21641846.2015.1023652
  14. Bateman, L.; Darakjy, S.; Klimas, N.; Peterson, D.; Levine, S.M.; Allen, A.; Carlson, S.A.; Balbin, E.G.; Gottschalk, G.; March, D. (2015), "Chronic fatigue syndrome and co-morbid and consequent conditions: evidence from a multi-site clinical epidemiology study", Fatigue: Biomedicine, Health & Behavior, 3 (1): 1-15, doi:10.1080/21641846.2014.978109
  15. Hornig, M; Montoya, JG; Klimas, NG; Levine, SM; Felsenstein, D; Bateman, L; Peterson, DL; Gottschalk, CG; Schultz, AF; Che, X; Eddy, ML; Komaroff, AL; Lipkin, WI (2015). "Distinct plasma immune signatures in ME/CFS are present early in the course of illness". Science Advances. 1 (1). doi:10.1126/sciadv.1400121.
  16. Giloteaux, Ludovic; Goodrich, Julia K.; Walters, William A.; Levine, Susan M.; Ley, Ruth E.; Hanson, Maureen R. (December 2016). "Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome". Microbiome. 4 (1): 30. doi:10.1186/s40168-016-0171-4. ISSN 2049-2618. PMC 4918027. PMID 27338587.
  17. Nagy-Szakal, Dorottya; Williams, Brent L.; Mishra, Nischay; Che, Xiaoyu; Lee, Bohyun; Bateman, Lucinda; Klimas, Nancy G.; Komaroff, Anthony L.; Levine, Susan; Montoya, Jose G.; Peterson, Daniel L.; Ramanan, Devi; Jain, Komal; Eddy, Meredith L.; Hornig, Mady; Lipkin, W. Ian (2017), "Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome", Microbiome, 5 (44), doi:10.1186/s40168-017-0261-y
  18. Germain, Arnaud; Ruppert, David; Levine, Susan M.; Hanson, Maureen R. (2017), "Metabolic profiling of a myalgic encephalomyelitis/chronic fatigue syndrome discovery cohort reveals disturbances in fatty acid and lipid metabolism", Molecular BioSystems (2), doi:10.1039/C6MB00600K
  19. Montoya, Jose G; Anderson, Jill N; Adolphs, Danya L; Bateman, Lucinda; Klimas, Nancy; Levine, Susan M; Garvert, Donn W; Kaiser, Jon D (2018), "KPAX002 as a treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A prospective, randomized trial" (PDF), International Journal of Clinical and Experimental Medicine, 11 (3): 2890-2900
  20. Mandarano, AH; Giloteaux, L; Keller, BA; Levine, SM; Hanson, MR (2018), "Eukaryotes in the gut microbiota in myalgic encephalomyelitis/chronic fatigue syndrome", PeerJ, 6: e4282, doi:10.7717/peerj.4282
  21. Nagy-Szakal, Dorottya; Barupal, Dinesh K.; Lee, Bohyun; Che, Xiaoyu; Williams, Brent L.; Kahn, Ellie J.R.; Ukaigwe, Joy E.; Bateman, Lucinda; Klimas, Nancy G.; Komaroff, Anthony L.; Levine, Susan; Montoya, Jose G.; Peterson, Daniel L.; Levin, Bruce; Hornig, Mady; Fiehn, Oliver; Lipkin, W. Ian (2018), "Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics", Scientific Reports, 8 (1): 10056, doi:10.1038/s41598-018-28477-9
  22. Germain, Arnaud; Ruppert, David; Levine, Susan M.; Hanson, Maureen R. (December 2018). "Prospective Biomarkers from Plasma Metabolomics of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Implicate Redox Imbalance in Disease Symptomatology". Metabolites. 8 (4): 90. doi:10.3390/metabo8040090.
  23. Dimmock, Mary; Devine, Susan; Wilder, Terri L. "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: What Every Family Physician Needs to Know" (PDF). Family Doctor: A Journal of the New York State Academy of Family Physicians. 6 (3): 23–25.
  24. Germain, Arnaud; Barupal, Dinesh K.; Levine, Susan M.; Hanson, Maureen R. (January 14, 2020). "Comprehensive Circulatory Metabolomics in ME/CFS Reveals Disrupted Metabolism of Acyl Lipids and Steroids". Metabolites. 10 (1): 34. doi:10.3390/metabo10010034. ISSN 2218-1989.
  25. Giloteaux, Ludovic; O'Neal, Adam; Castro-Marrero, Jesús; Levine, Susan M.; Hanson, Maureen R. (December 2020). "Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/chronic fatigue syndrome: a pilot study". Journal of Translational Medicine. 18 (1): 387. doi:10.1186/s12967-020-02560-0. ISSN 1479-5876. PMC 7552484.
  26. Germain, Arnaud; Giloteaux, Ludovic; Moore, Geoffrey E.; Levine, Susan M.; Chia, John K.; Keller, Betsy A.; Stevens, Jared; Franconi, Carl J.; Mao, Xiangling; Shungu, Dikoma C.; Grimson, Andrew (March 31, 2022). "Plasma metabolomics reveals disrupted response and recovery following maximal exercise in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". JCI Insight. doi:10.1172/jci.insight.157621. ISSN 0021-9738.